Aftab Ahmad

Sarwar Beg

Mahfoozur Rahman

Hani Choudhry

Mazin A. Zamzami

Khalid S. Alharbi

This new volume looks at the applications of biomarkers as important tools for herbal drug discovery, presenting research on phytoconstituents with advanced nanotechnological applications for healthcare benefits. Herbal drug discovery based on biomarkers is an emerging area in complementary and alternative medicine that has tremendous potential in healthcare. Conventional medications have limited efficacy and high toxicity, whereas herbal drugs are said to provide wide structural diversity that is not usually seen with conventional/synthetic drug molecules. Recognition of various herbal constituents, such as terpenoids, fatty acids, flavonoids and steroids, are well explored in the management and treatment of various disorders in this volume. These agents target various biomarkers such as nitric oxide (NO), cytokines, chemokines, adhesion molecules, NF- kβ, lipoxygenase (LOX), and arachidonic acid. Biomarkers as Targeted Herbal Drug Discovery: A Pharmacological Approach to Nanomedicines discusses phytoconstituent-based nanotherapeutics with applications for some specific health issues, such as arthritis, leishmanicidal, cardiovascular diseases, cancer, ocular disorders, etc.

A Pharmacological Approach to Nanomedicines

Biomarkers as Targeted Herbal Drug Discovery

Zulqurnain Khan

Sultan Habibullah Khan

This book discusses CRISPR/Cas- one of the most powerful tools available to scientists for genome editing. CRISPR/Cas is not only a genome editing tool, but researchers have also engineered it for gene regulation, genome imaging, base editing and epigenome regulations. This book describes the entire toolkit for CRISPR/Cas. The opening section gives an introduction to the technique and compares it with other genome editing tools. Further section gives a historical perspective of the tool, along with its detailed classification. The next chapters describe bioinformatic tools in CRISPR/Cas, and delivery methods for CRISPR/Cas. The book also discusses about the applications of CRISPR/Cas beyond genome editing and use of CRISPR for rewriting genetic codes. The book dedicates a section to the use of CRISPR in plants. The book culminates with a chapter on the current status, challenges and shortcomings of the CRISPR/Cas genome editing tool. The book would be highly interesting to students and researchers in molecular biology, biochemistry, biotechnology, food science, agriculture and plant sciences.

The CRISPR/Cas Tool Kit for Genome Editing

This book compiles the latest applications of the cutting-edge gene editing tool CRISPR/Cas in the area of crop improvement. It begins with an introduction to the technique and its application in crop plants. Next, it gives an updated overview of available delivery methods, design tools and resources in CRISPR/Cas. The book subsequently reviews the applications of CRISPR/Cas in connection with e.g. insect stress, disease stress, abiotic stress, nutritional and yield improvement in crop plants, etc. It also discusses the various regulatory, ethical and social aspects of the technique that must be kept in mind when designing experiments. In closing, the book summarizes the status quo and outlines future prospects for the tool in crop improvement and food security. Given its scope, the book will especially benefit students and researchers in food science, biotechnology, agriculture and the plant sciences.

The Future of Food Security

CRISPR Crops

Matt Reeck

Freshly arrived in 1930s Bombay, Manto saw the city like no one else, an ethnic melting pot that became ever more varied as migrant workers flooded in. It was to be Manto’s favourite city. His edgy, moving stories, often peopled with prostitutes and criminals, remain startling and provocative even a hundred years after his birth – in searching out those forgotten by humanity, Manto wrote about what it means to be human. At his centenary, Bombay Stories brings together Manto’s work from his years in that city for the first time. Matt Reeck and Aftab Ahmad’s contemporary, nuanced translation captures the idiom and the essence of Urdu’s most celebrated short-story writer’s work. Censored, banned, demonized and ostracized: Saadat Hasan Manto’s short stories were considered obscene and downright dangerous during his lifetime and for years after. They still haven’t lost their power to shock and enthrall.

Aftab Ahmad

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