Alan Boobis

Lucia Anelich

Michael E. Knowles

Bert Popping

Present Knowledge in Food Safety: A Risk-Based Approach Through the Food Chain presents approaches for exposure-led risk assessment and the management of changes in the chemical, pathogenic microbiological and physical (radioactivity) contamination of ’food’ at all key stages of production, from farm to consumption. This single volume resource introduces scientific advances at all stages of the production to improve reliability, predictability and relevance of food safety assessments for the protection of public health. This book is aimed at a diverse audience, including graduate and post-graduate students in food science, toxicology, microbiology, medicine, public health, and related fields. The book's reach also includes government agencies, industrial scientists, and policymakers involved in food risk analysis. Includes new technologies such as nanotechnology, genetic modification, and cloning Provides information on advances in pathogen risk assessment through novel and real-time molecular biological techniques, biomarkers, resistance measurement, and cell-to-cell communication in the gut Covers the role of the microbiome and the use of surrogates (especially for viruses)

A Risk-Based Approach Through the Food Chain

Present Knowledge in Food Safety

Michael Knowles

Present Knowledge in Food Safety: A Risk-Based Approach Through The Food Chain presents exposure-led risk assessment and management of changes in chemical, pathogenic microbiological and physical (radioactivity) contamination of 'food' at all key stages of production from farm to consumption. Within this framework, the book takes a holistic approach to food safety and its regulation, and to the identification of hazard control points. This is a single volume resource which introduces scientific advances to improve the reliability, predictability, and relevance of food safety assessments for the protection of public health. This includes mechanistic (ADMET) studies, e.g. based on developments in the pharmaceutical industry; validation of in vitro / in silico / -omics methods and probabilistic approaches to exposure analysis including uncertainty and aggregate exposure analysis for the general population and vulnerable sub-groups. The book is, therefore, aimed at a diverse audience, including graduate and post-graduate students in food science, toxicology, microbiology, medicine, public health, and related fields. The audience will also include government agencies, industrial scientists, and policy makers involved in food risk analysis. Includes new technologies such as nanotechnology, genetic modification, and cloning will be addressed along with discussions of consumer concerns Provides information on advances in pathogen risk assessment through real-time DNA analyses, biomarkers, resistance measurement, cell-to-cell communication in the gut Covers the role of the microbiome and the use of surrogates (especially for viruses)

Alan Boobis

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