Aslak Tveito

Kent-Andre Mardal

Joakim Sundnes

Glenn Terje Lines

Xing Cai

Bjørn Frederik Nielsen

This book describes mathematical models and numerical techniques for simulating the electrical activity in the heart. It gives an introduction to the most important models, followed by a detailed description of numerical techniques. Particular focus is on efficient numerical methods for large scale simulations on both scalar and parallel computers. The results presented in the book will be of particular interest to researchers in bioengineering and computational biology.

Computing the Electrical Activity in the Heart

Hans Petter Langtangen

A gentle introduction to advanced topics such as parallel computing, multigrid methods, and special methods for systems of PDEs. The goal of all chapters is to ‘compute’ solutions to problems, hence algorithmic and software issues play a central role. All software examples use the Diffpack programming environment - some experience with Diffpack is required. There are also some chapters covering complete applications, i.e., the way from a model, expressed as systems of PDEs, through to discretization methods, algorithms, software design, verification, and computational examples. Suitable for readers with a background in basic finite element and finite difference methods for partial differential equations.

Numerical Methods and Diffpack Programming

Advanced Topics in Computational Partial Differential Equations

Ragnar Winther

Combining both the classical theory and numerical techniques for partial differential equations, this thoroughly modern approach shows the significance of computations in PDEs and illustrates the strong interaction between mathematical theory and the development of numerical methods. Great care has been taken throughout the book to seek a sound balance between these techniques. The authors present the material at an easy pace and exercises ranging from the straightforward to the challenging have been included. In addition there are some "projects" suggested, either to refresh the students memory of results needed in this course, or to extend the theories developed in the text. Suitable for undergraduate and graduate students in mathematics and engineering.

A Computational Approach

Introduction to Partial Differential Equations

Marie E. Rognes

This open access volume presents a novel computational framework for understanding how collections of excitable cells work. The key approach in the text is to model excitable tissue by representing the individual cells constituting the tissue. This is in stark contrast to the common approach where homogenization is used to develop models where the cells are not explicitly present. The approach allows for very detailed analysis of small collections of excitable cells, but computational challenges limit the applicability in the presence of large collections of cells.

The EMI Framework

Modeling Excitable Tissue

Olav Lysne

Are Magnus Bruaset

When researchers gather around lunch tables, at conferences, or in bars, there are some topics that are more or less compulsory. The discussions are about the ho- less management of the university or the lab where they are working, the lack of funding for important research, politicians’ inability to grasp the potential of a p- ticularly promising ?eld, and the endless series of committees that seem to produce very little progress. It is common to meet excellent researchers claiming that they have almost no time to do research because writing applications, lecturing, and - tending to committee work seem to take most of their time. Very few ever come into a position to do something about it. With Simula we have this chance. We were handed a considerable annual grant and more or less left to ourselves to do whatever we thought would produce the best possible results. We wanted to create a place where researchers could have the time and conditions necessary to re?ect over dif?cult problems, uninterrupted by mundane dif?culties; where doctoral students could be properly supervised and learn the craft of research in a well-organized and professional manner; and where entrepreneurs could ?nd professional support in developing their research-based - plications and innovations.

by Thinking Constantly about it

Simula Research Laboratory

Aslak Tveito

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