Barbara J. Bain

UP-TO-DATE PRACTICAL GUIDE TO LEUKAEMIA DIAGNOSIS Written by a renowned expert this practical guide had been fully revised and updated. The book covers recent advances in the fields of immunophenotyping, cytogenetics and molecular genetics. It illustrates how laboratory techniques are used for the diagnosis and classification of leukaemia and includes images of abnormal cells to aid diagnosis. This fifth edition: Incorporates the recommendations of the 2015 WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues Includes 300 high quality full colour digital images of abnormal cells in leukaemia and lymphoma Full colour diagrams and helpful tables clarify and summarise key points throughout Essential reading for every haematologist and haematopathologist.

Leukaemia Diagnosis

A Beginners Guide to Blood Cells

Mike A Laffan

Imelda Bates

S. Mitchell Lewis

Highly Commended at 2012 BMA awards in Internal Medicine Category. Recognized worldwide as the standard reference work, Dacie & Lewis Practical Haematology is a must have reference for any haematology laboratory. It covers all of the techniques used in the investigation of patients with blood disorders, including the latest technologies as well as the tried and true manual methods of measurement. It discusses the principles of each test, possible causes of error, the rationale for choosing one method over another and the interpretation, significance and clinical relevance of these findings. Each chapter conforms to a template, providing quick access to key information

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Dacie and Lewis Practical Haematology

Barbara Wild

Adrian Stephens

Lorraine Phelan

Variant Haemoglobins – A Guide to Identification is based on the premise that any single diagnostic technique offers only a very provisional identification of a variant haemoglobin. In routine diagnostic practice two techniques are needed as a minimum, with the results being interpreted in the light of the clinical details, blood count, blood film and ethnic origin. This book covers 150 normal and variant haemoglobins that have been studied and carefully documented. Variant Haemoglobins has four introductory chapters followed by an invaluable atlas. The introductory chapters cover the genetics of haemoglobin synthesis the principles of tests employed for identification common haemoglobins of major clinical or diagnostic importance thalassaemias and related conditions The atlas section comprises 170 full colour pages in which each variant haemoglobin or combination of haemoglobins is illustrated by cellulose acetate electrophoresis at alkaline pH, agarose gel electrophoresis at acid pH, isoelectric focusing and one or more HPLC traces. For ease of reference, the atlas pages are arranged according to the retention time of each haemoglobin on HPLC, this becoming increasingly the primary technique employed in haemoglobin identification. Bringing a mix of necessary scientific expertise and clinical knowledge, each author has more than 30 years experience in the diagnosis of variant haemoglobins. Providing otherwise unavailable information, this unique and practical guide is illustrated with over 700 high quality colour digital images plus flow charts and line diagrams covers common and important haemoglobin variants, in addition to many rarer ones is an essential reference source for diagnosis in the haematology laboratory A remarkably useful book, Variant Haemoglobins will be valuable for haematopathologists, clinical and laboratory haematologists in practice and in training and all laboratory staff involved in haemoglobinopathy diagnosis.

A Guide to Identification

Variant Haemoglobins

David M. Clark

Bridget S. Wilkins

Irvin A. Lampert

Written by one of the world's leading haematologists, and three renowned histopathologists, Bone Marrow Pathology provides a comprehensive guide to the diagnosis of bone marrow disease. Now in its Third Edition, the text has been extensively revised and rewritten to reflect the latest advances in the field. Features: An extremely practical, up-to-the-minute text incorporating the new WHO classification of haematopoietic malignancies A comprehensive text written with great precision and clarity of style Incorporates a new section 'Problems and Pitfalls' - a unique section that will aid the working pathologist faced with a difficult situation An important text for the haematologist, histopathologist and haematopathologist with equal weight given to peripheral blood, aspirate, trephine biology and specialized techniques Extensively illustrated with many of the photographs being of paraffin-embedded sections Combines all the techniques now applied to bone marrow diagnosis, including immunocytochemistry, flow cytometery, immunohistochemistry and the diagnostic role of cytogenetic and molecular genetic analysis

Bone Marrow Pathology

Bone Marrow Pathology has been extensively revised to reflect the significant advances which have occurred in the application of cytogenetics and in particular, molecular genetics in the diagnosis, classification and understanding of haematological disorders. This comprehensive book not only provides information on all common disease entities, but also covers rare disorders in which bone marrow examination is useful. It is designed as a practical resource with "problems and pitfalls" highlighted throughout to aid laboratory diagnosis.

Durante más de 65 años, este éxito de ventas de los doctores Barbara Bain, Imelda Bates y Mike A. Laffan, ha sido la referencia en todo el mundo en hematología de laboratorio. Internacionalmente reconocida como la obra de referencia para los laboratorios de hematología, este manual práctico describe todas las técnicas utilizadas en la investigación de los pacientes con enfermedades sanguíneas. Analiza los principios de cada prueba, las causas posibles de error, el razonamiento para elegir un método u otro y la interpretación, significado e importancia clínica de los resultados. Aborda las últimas tecnologías y procedimientos en el trabajo de laboratorio. Incluye nueva información sobre seguridad en el laboratorio, proporcionando una guía sobre los riesgos de cada procedimiento. Hace hincapié en los detalles técnicos de los métodos, junto con una perspectiva crítica sobre su interpretación y utilidad clínica. Ofrece directrices útiles a todos los niveles, desde los centros primarios de salud, donde solo se realizan unas pocas pruebas diagnósticas, hasta centros especializados con tecnología sofisticada. Proporciona árboles de decisión que ayudan a enfrentarse a diversas situaciones clínicas desde el punto de vista de los análisis de laboratorio. Incluye capítulos sobre organización, dirección y control de calidad del laboratorio. Dispone de contenido adicional en ExpertConsult que permite búsquedas en todo el texto y referencias en una gran variedad de dispositivos.

Dacie Y Lewis. Hematología Práctica

S. N. Wickramasinghe

Blood and Bone Marrow

Blood Cells has been written with both the practising haematologist and the trainee in mind. It aims to provide a guide for use in the diagnostic haematology laboratory, covering methods of collection of blood specimens, blood film preparation and staining, the principles of manual and automated blood counts and the assessment of the morphological features of blood cells. The practising haematologist should find this book sufficiently comprehensive to be a reference source while, at the same time, the trainee haematologist and biomedical scientist should find it a straightforward and practical bench manual. Enables both the haematologist and laboratory scientist to identify blood cell features, from the most common to the more obscure Provides essential information on methods of collection, blood film preparation and staining, together with the principles of manual and automated blood counts Completely revised and updated, incorporating much newly published information: now includes advice on further tests when a specific diagnosis is suspected Four hundred high quality photographs to aid with blood cell identification Highlights the purpose and clinical relevance of haematology laboratory tests throughout

A Practical Guide

Blood Cells

The nature of leukaemia, cytology, cytochemistry and the morphological classification -- Immunophenotyping and cytogenetic/molecular genetic analysis -- Acute myeloid leukaemia, integration of morphological, immunophenotypic and genetic information and the WHO classification -- Acute lymphoblastic leukaemia and acute leukaemia of ambiguous lineage -- The myelodysplastic syndromes and the myelodysplastic/myeloproliferative neoplasms -- Chronic myeloid leukaemias -- Lymphoid leukaemias of mature T, B, and natural killer cells -- Leukaemia diagnosis in resource-poor countries

Bone Marrow Pathology has been extensively revised to reflect the significant advances which have occurred in the application of cytogenetics and in particular, molecular genetics in the diagnosis, classification and understanding of haematological disorders. This comprehensive book not only provides information on all common disease entities, but also covers rare disorders in which bone marrow examination is useful. It is designed as practical resource with ‘Problems and Pitfalls’ sections throughout to aid laboratory diagnosis. This fourth edition: Incorporates the recommendations of the 2008 WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues Covers key diagnostic techniques such as flow cytometric immunophenotyping, immunohistochemistry and cytogenetic and molecular genetic analysis Includes new diagnostic algorithms and summary boxes Contains 550 colour illustrations including high-quality digital photomicrographs Haematologists and histopathologists will find this book an invaluable desktop reference when performing daily blood and bone marrow investigations.

The blood film and count -- Assessing red cells -- Assessing white cells and platelets -- Haematological findings in health and disease -- Emergency morphology -- Self-assessment

A Beginner's Guide to Blood Cells

Bob Jackson

Allyson Doig

Mike Leach

Pam McKay

Mark Drummond

"Provide a practical, example-based resource for flow cytometry"--Provided by publisher.

100 Worked Examples

Practical Flow Cytometry in Haematology

This popular pocket book has been updated and expandedthroughout, providing a concise view of diagnostic haematology, ina convenient and practical format. A Beginner's Guide to Blood Cells is an idealfor; Trainee laboratory technicians and scientists Students studying the physiology or pathology of theblood Those preparing for haematology examinations Why Buy This Book? Unique pocket guide, written by Barbara Bain – aworld-renowned expert in the field of blood morphology Outlines the basics of diagnostic haematology Includes an invaluable self-assessment section NEW EDITION – now includes more information onclinical aspects and further tests

For more than 65 years, this best-selling text by Drs. Barbara J. Bain, Imelda Bates, and Mike A. Laffan has been the worldwide standard in laboratory haematology. The 12th Edition of Dacie and Lewis Practical Haematology continues the tradition of excellence with thorough coverage of all of the techniques used in the investigation of patients with blood disorders, including the latest technologies as well as traditional manual methods of measurement. You’ll find expert discussions of the principles of each test, possible causes of error, and the interpretation and clinical significance of the findings. A unique section on haematology in under-resourced laboratories. Ideal as a laboratory reference or as a comprehensive exam study tool. Each templated, easy-to-follow chapter has been completely updated, featuring new information on haematological diagnosis, molecular testing, blood transfusion- and much more. Complete coverage of the latest advances in the field. An expanded section on coagulation now covers testing for new anticoagulants and includes clinical applications of the tests.

Barbara J. Bain

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