Christian Klein

John P. Sullivan

Tianshu Liu

Keisuke Asai

Yasuhiro Egami

This new edition describes pressure and temperature sensitive paints (PSP and TSP) in global surface pressure and temperature measurements in aerodynamics and fluid mechanics. The book includes the latest progress in paint formulations, instrumentation, and steady and unsteady aerodynamic measurements in various facilities including low-speed, transonic, supersonic and hypersonic wind tunnels. The updated technical aspects of PSP and TSP in the book will be useful for students and researchers in experimental aerodynamics and fluid mechanics.

Pressure and Temperature Sensitive Paints

eine formgeschichtliche Studie

Kohelet und die Weisheit Israels

Jean-Claude Saut

Nonlinear Dispersive Equations are partial differential equations that naturally arise in physical settings where dispersion dominates dissipation, notably hydrodynamics, nonlinear optics, plasma physics and Bose-Einstein condensates. The topic has traditionally been approached in different ways, from the perspective of modeling of physical phenomena, to that of the theory of partial differential equations, or as part of the theory of integrable systems. This monograph offers a thorough introduction to the topic, uniting the modeling, PDE and integrable systems approaches for the first time in book form. The presentation focuses on three "universal" families of physically relevant equations endowed with a completely integrable member: the Benjamin-Ono, Davey-Stewartson, and Kadomtsev-Petviashvili equations. These asymptotic models are rigorously derived and qualitative properties such as soliton resolution are studied in detail in both integrable and non-integrable models. Numerical simulations are presented throughout to illustrate interesting phenomena. By presenting and comparing results from different fields, the book aims to stimulate scientific interactions and attract new students and researchers to the topic. To facilitate this, the chapters can be read largely independently of each other and the prerequisites have been limited to introductory courses in PDE theory.

Inverse Scattering and PDE Methods

Nonlinear Dispersive Equations

Brian H. Santich

Nai-Kong Cheung

CK is affiliated with the Roche Innovation Center Zurich, holds stocks and has patents with Hoffmann-La Roche company. NKC reports receiving commercial research grants from Y-mabs Therapeutics and Abpro-Labs Inc.; holding ownership interest/equity/options in Y-Mabs Therapeutics Inc., and in Abpro-Labs, and owning stock options in Eureka Therapeutics. NKC is the inventor of pending and issued patents filed by MSK, including hu3F8 and 8H9 licensed to Ymabs Therapeutics, beta-glucan to Biotec Pharmacon, and HER2 bispecific antibody to Abpro-labs. NKC is an advisory board member for Abpro-Labs and Eureka Therapeutics

Bispecific Antibodies for T-Cell Based Immunotherapy

Matías Martínez

Erzählen als grundlegende Form der Wirklichkeitserkenntnis und des sozialen Verhaltens. In vielen Bereichen des Alltags orientieren und verständigen wir uns mithilfe von Erzählungen. Der interdisziplinäre Band liefert einen systematischen Überblick über die wichtigsten Felder des nicht-literarischen Erzählens in Institutionen und im Alltag: z.B. Journalismus, Medizin, Psychologie, Recht, Religion und Wirtschaft.

Felder, Formen und Funktionen nicht-literarischen Erzählens

Wirklichkeitserzählungen

This book is a printed edition of the Special Issue "Monoclonal Antibodies" that was published in Antibodies

Monoclonal Antibodies

Julia Abel

Diese Einführung liefert einen Überblick über die historisch-kulturellen, theoretischen und analytischen Dimensionen der Beschäftigung mit Comics und Graphic Novels und ist dabei gleichermaßen systematisch wie praxisbezogen ausgerichtet. So informieren ausgewiesene Experten in Einzelbeiträgen etwa über medientheoretische Aspekte, Fragen der besonderen Produktion, Distribution und Rezeption von Comics, über zentrale Genres und ihre Klassiker und stellen ein handhabbares Instrumentarium zur Comic-Analyse vor. Abgerundet wird der Band durch Ausführungen zu Web-Comics und zu Institutionen der Comic-Forschung, durch ein Glossar und kommentierte Hinweise zur Fachliteratur bei jedem Beitrag. Mit Beiträgen von Julia Abel, Jochen Ecke, Barbara Eder, Christian Endres, Lukas Etter, Ole Frahm, Björn Hammel, Urs Hangartner, Matthias Harbeck, Christian Klein, Andreas C. Knigge, Stephan Köhn, Stephan Packard, Andreas Platthaus, Monika Schmitz-Emans, Marie Schröer, Daniel Stein, Ralph Trommer, Antonius Weixler, Lukas Werner

Eine Einführung

Comics und Graphic Novels

Biographie als allgegenwärtiges Phänomen. Das Handbuch informiert über die verschiedenen Formen und Felder biographischen Erzählens und macht mit Merkmalen und Funktionen, mit Geschichte, regionalen Entwicklungen und kulturellen Traditionen der Biographik vertraut. Daneben stellt es biographisches Arbeiten als wissenschaftliche Methode in den Geistes-, Sozial- und Kulturwissenschaften sowie in der Medizin vor. Eine Einführung in die Analyse biographischen Erzählens und Antworten auf grundlegende Praxisfragen runden die disziplinenübergreifende Darstellung ab.

Methoden, Traditionen, Theorien

Handbuch Biographie

János Fischer

Wayne E. Childers

Provides unique insider insight into the current drug development process, and what it takes to achieve success In this fourth volume in the series, inventors and primary developers of drugs that made it to the market continue telling the story of the drugs? discovery and development, and discuss the sometimes twisted route from the first drug candidate molecule to the final marketed one. Beginning with a general section addressing overarching topics for drug discovery, the book offers seven chapters that feature selected case studies describing recently introduced drugs or drug classes. These include small molecule drugs as well as biopharmaceuticals and range across different therapeutic fields. Together, they provide a representative cross-section of the present-day drug development effort. Successful Drug Discovery: Volume 4 covers trends in peptide-based drug discovery and the physicochemical properties of recently approved oral drugs. The section on drug class studies looks at antibody-drug conjugates and the discovery, evolution, and therapeutic potential of dopamine partial agonists. Featured case studies examine the discovery of Etelcalcetide for the treatment of secondary hyper-parathyroidism in patients with chronic kidney disease; the development of Lenvatinib Mesylate; the discovery and development of Venetoclax; and more. -Focuses on recently introduced drugs that have not been featured in any textbooks or general references, including Ocrelizumab, a new generation of anti-CD-20 mAb for the treatment of multiple sclerosis, and Venetoclax, a selective antagonist of BCL-2 -Features personal experiences of successful drug developers from industry and academia -Endorsed and supported by the International Union of Pure and Applied Chemistry (IUPAC) Successful Drug Discovery: Volume 4 provides a fascinating and informative look into the process of drug discovery and would be a great reference for those in the pharmaceutical industry, organic and pharmaceutical chemists, and lecturers in pharmacy.

Successful Drug Discovery

Franz-Josef Deiters

Zentraler Bestandteil der Erinnerungsdiskurse zum Ersten Weltkrieg sind jene Romane, Gedichte oder – historisch besonders wirkmächtig – Theaterstücke, die sich mit dem Kriegsgeschehen und dessen Auswirkungen auseinandersetzen. Der Band konzentriert sich auf die Verarbeitung des Kriegsgeschehens im deutschsprachigen und australischen Drama, weil dem Ersten Weltkrieg eine vergleichbar große Relevanz im jeweiligen Identitätsdiskurs zukommt, er aber gleichzeitig eine ganz unterschiedliche Akzentuierung erfährt. Die Weltkriegsdramatik erscheint vor diesem Hintergrund als idealer Gegenstand transnationaler komparatistischer Studien.

Christian Klein

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