Geralyn Lawrenson

David Evered

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Biological Roles of Copper

Julie Whelan

Derek Chadwick

Reviews recent basic research into IgE, mast cells, and the allergic response and the relevance of this work to human pathophysiology, and discusses new methods of treatment. This symposium is unique in the IgE field for its breadth of coverage and interdisciplinary nature, and it shows the benefits from the current rapid expansion of knowledge in cell biology, immunology, and molecular genetics, as well as the potential clinical significance of this research to clinical immunologists and allergologists.

IgE, Mast Cells and the Allergic Response

This work focuses on the autoimmune processes that have now been proven to underlie a number of serious diseases, including diabetes mellitus, rheumatoid arthritis and multiple sclerosis. Papers explore the rapidly expanding developments in research on immune response and regulation, and their potential in the development of treatments for autoimmune diseases. The wide range of subjects covered here include: the nature of intracellular and cell surface-derived ``self'' antigens; competing theories of the generation of immune tolerance and their implications of current theories for research and treatment; possible links between autoimmunity and genetic complement deficiency; the contributions of interferons and class II HLA antigen expression to autoimmunity; and the potential of monoclonal antibodies and other biotechnological advances in treating human autoimmune conditions.

Autoimmunity and Autoimmune Disease

Maeve O'Connor

Neuropharmacology of Insects

Derek J. Chadwick

Geralyn M. Collins

Cytopathology of Parasitic Disease

Sarah Clark

A multidisciplinary volume presenting recent research relating to papillomaviruses and their association with certain types of malignant lesions. Presents up-to-date findings on their classification and their molecular biology and cell-virus interactions, including mode of entry, modification of genetic material and pathogenecity; their relationship to various kinds of skin conditions; their association with cervical carcinoma and carcinomas of the bladder and alimenatry tract, with descriptions of in vitro studies; and finally, their immunology and possible therapeutic agents, e.g., interferon and vaccination. The only comprehensive text on the subject, it brings together the work of many of the most prominent researchers in the field.

Papillomaviruses

Silicon Biochemistry

A provocative challenge at a dinner party, a serendipitous encounter on a Northumberland cliff top, the accidental death of a friend and the rupture of his marriage converge to disrupt Peter Bowman’s well-ordered middle-class existence as he approaches middle age. Peter negotiates a sabbatical from his job as a solicitor to pursue his long held ambition to write fiction. He embarks on an odyssey which leads him to new challenges and loves shaped by happiness and tragedy. When Peter goes to France to stay with Sally, an enigmatic freelance journalist with a troubled past, he takes the first tentative steps towards writing a novel. But can he, as a member of the pre-baby boomer generation, ever fully escape from the constraints imposed by his background and upbringing and embrace the liberal and permissive attitudes of the 1960s and achieve his lifelong ambition? Inspired by modern writers including Sebastian Faulks, Kate Atkinson and Julian Barnes, Beyond the Arch is the debut novel from David Evered which explores the changing society and culture of the late 1960s. The book will appeal to readers that enjoy contemporary fiction, as well as those interested in relationships.

Beyond the Arch

Sara Harnett

Comprises the proceedings of a symposium held at the Ciba Foundation, March 1988. Contributors present an international, interdisciplinary approach to the biology and biological chemistry of cyanide and related compounds. Addressed are the microbial metabolism of HCN and organic nitrile compounds, cyanogenesis in higher plants, qualitative and quantitative methods of analysis of cyanogenic glycosides, and detoxification of hydrogen cyanide by animals.

David Evered

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