David M. Glover

Christopher Hutchison

The use of developing technologies has revealed the extraordinary degree to which cell cycle control mechanisms have been conserved through eukaryotic evolution. This monograph relates the current scientific understanding of cell cycle control.

Cell Cycle Control

Genetic Engineering Cloning DNA

Alan Hall

Cell Biology of Cancer

This is a textbook on modelling, data analysis and numerical techniques for advanced students and researchers in chemical, biological, geological and physical oceanography.

Modeling Methods for Marine Science

B. D. Hames

This new addition to the Frontiers in Molecular Biology series, written by internationally known experts, provides a detailed account of the current knowledge in this rapidly changing field. A useful alternative to multiple sources, this text provides in-depth coverage of such topics as the molecular biology of receptors and ion channels, as well as the use of Drosophila as a neurological model. More than just a collection of articles, this carefully edited volume gives the reader a wealth of up-to-date information in a lively, cohesive format.

Molecular Neurobiology

William J. Jenkins

Scott C. Doney

This advanced textbook on modeling, data analysis and numerical techniques for marine science has been developed from a course taught by the authors for many years at the Woods Hole Oceanographic Institute. The first part covers statistics: singular value decomposition, error propagation, least squares regression, principal component analysis, time series analysis and objective interpolation. The second part deals with modeling techniques: finite differences, stability analysis and optimization. The third part describes case studies of actual ocean models of ever increasing dimensionality and complexity, starting with zero-dimensional models and finishing with three-dimensional general circulation models. Throughout the book hands-on computational examples are introduced using the MATLAB programming language and the principles of scientific visualization are emphasised. Ideal as a textbook for advanced students of oceanography on courses in data analysis and numerical modeling, the book is also an invaluable resource for a broad range of scientists undertaking modeling in chemical, biological, geological and physical oceanography.

Ignacio Pérez de Castro

Mar Carmena

Claude Prigent

Aurora kinases are key mitotic regulators that have also been associated with tumor development and progression. The interest on this highly conserved family of protein kinases has grown exponentially since they were discovered in the 1990s. Despite the steady increase in the number of laboratories involved and the consequent boost of the volume of research output during the last years, the study of Aurora kinases remains a very dynamic area in which new discoveries frequently keep coming to light. In this Frontiers Research Topic, we have aimed to not only review and revisit different aspects of the functions and regulation of Aurora kinases but also provide a forum for the publication of new developments in the field. Thanks to the excellent work of the authors and reviewers of this eBook, which includes some of the most experienced voices in the field, we hope that this collection will inspire new research projects that will lead to a better understanding of the role of these kinases in cancers.

Aurora Kinases: Classical Mitotic Roles, Non-Canonical Functions and Translational Views

Department of Biochemistry and Molecular Biology B D Hames

This book gives a co-ordinated review of our present knowledge of eukaryotic RNA synthesis.

Transcription and Splicing

The principles of cloning DNA; Recombination and mutagenesis of DNA in vitro; Bacteriophage vectors; Bacterial plasmid vectors; Expression of cloned DNAs in E. coli plasmids; The physical characterization of cloned DNA segments and their counterparts within chromosomes; Gene cloning in fungi and plants; Expression of cloned genes in animal cells.

David M. Glover

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