Gautam Sethi

Manoj Garg

Amit Kumar Pandey

Transcription and Translation in Health and Disease provides a detailed overview of the regulators underlying transcription and translation in relation to a variety of human diseases and disorders. Beginning with an introduction into the current perspectives relating to these processes in human disease, the book expands to focus on specific mechanisms underlying conditions such as arthritis, cancer, neurological disorders, diabetes and cardiovascular disease. This book considers RNA processing and related mechanisms in eukaryotes including RNA splicing, RNA binding proteins, RNA interference, microRNAs, RNA editing, transcription factors, RNAi screening, CRISPR activation, CRISPR-Cas9 interference, and post-translational modifications. It provides a structured and detailed overview of the various regulators underlying molecular processes and their impact on health and disease, equipping readers with the necessary knowledge for further investigation in the areas of treatment and therapeutic intervention. Discusses the role played by transcription and translational regulation in various diseases, including cancer, diabetes, cardiovascular disease and neurological disease Considers a range of post-transcriptional regulators, including RNA-binding proteins, non-coding RNAs, epigenetic modifiers, alternative splicing and telomerase-binding proteins Covers the topic from fundamental knowledge to the latest developments in clinical application Includes a section dedicated to therapeutic applications

Transcription and Translation in Health and Disease

This book will motivate you to Live Your Passion. It shows how the author, with the attitude of a racer and a mindset of a monk, was able to live his dream. It showcases the reader the thrilling world of Motorsports and throws light on the concept of Car Rallying in India. It will help you to prepare and participate and also give an insight about the major car rallies held in India. You will also know about the life transforming lessons the author learnt from rallying. Garnished with some poetry, it makes an interesting read. This book will motivate you to build immense confidence in achieving success in all fields of life!

Gautam Sethi

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