Gordon M. Shepherd

Challenging the belief that the sense of smell diminished during human evolution, Shepherd argues that this sense, which constitutes the main component of flavor, is far more powerful and essential than previously believed. --from publisher description.

How the Brain Creates Flavor and why it Matters

Neurogastronomy

A pioneer of neurogastronomy writes an engaging treatment of the brain's role in creating the taste of wine.

How the Brain Creates the Taste of Wine

Neuroenology

Marcus E. Raichle

Angelo Mosso's Circulation of Blood in the Human Brain

Gary Lynch

Ira B. Black

Herbert P. Killackey

with commentaries by Gordon M. Shepherd, Ira B. Black, and Herbert P. Killackey For years memory research focused on the neuron as the basic element of the brain, but developments in cognitive science now challenge the neurobiologist to understand the function of neural networks, perhaps one of the most difficult problems of the mind. This monograph articulates the ways in which neurobiologic discoveries can be interpreted in terms of psychological memory. The brain mechanisms of learning and memory have been extensively studied by both neuroscientists and psychologists in recent years. Here Gary Lynch outlines the main issues in this dialogue: using the olfactory cortex and related hippocampus as examples, he discusses the physiological and chemical process involved in producing long-term memory and the anatomical organization of the neuronal circuitries in which they are stored. Then, combining these arguments, Lynch arrives at a series of postulates about the dynamics of the formation, association, and recall of memory representations in cortical networks. An evolutionary theme concerning the origins of the hypothesized organizations and processes runs throughout the monograph. Commenting on some of these ideas, Gordon Shepherd (Yale University) takes up the ways particular aspects of cortical cells, the apical dendrites of pyramidal cells, can be active in storing information. Ira Black (Cornell University Medical College) discusses the biochemical mutability of individual neurons and how this must be taken into account in modeling the way neural cells support mnemonic processes. A general discussion of cortical morphology and memory is provided by Herbert Killackey (University of California, Irvine). Gary Lynch is at the Center for the Neurobiology of Learning and Memory, University of California, Irvine. Synapses, Circuits, and the Beginnings of Memoryinaugurates The Cognitive Science Institute Monographs Series, edited by Michael A. Gazzaniga. A Bradford Book.

Synapses, Circuits, and the Beginnings of Memory

Introduction: Why study history? Why the 1940s and 1950s? -- Genes: starting with DNA -- Signaling molecules: the first growth factor -- Signaling molecules: the first neurotransmitters in the brain -- Cell biology and the synapse -- Physiology: the action potential -- Physiology: synaptic potentials and receptor potentials -- Functional organization of neurons and dendrites -- Neural circuits: spinal cord, retina, invertebrate systems -- Neural circuits: cortical columns and cortical processing -- Neural systems: the neural basis of behavior -- Learning and memory: Donald Hobb, Brenda Milner and H.M. -- Neurology: foundations of brain imaging -- Neurosurgery: from Cushing to Penfield -- Neuropsychiatry: the breakthrough in psychopharmacology -- Theoretical neuroscience: the brain as a computer and the computer as a brain -- Summing up -- Appendix A: Resources -- Appendix B: Supporting material available on the web.

Creating Modern Neuroscience: The Revolutionary 1950s

Cover -- Foundations of the Neuron Doctrine -- Copyright -- Dedication -- Contents -- Preface to the 25th Anniversary Edition -- Preface to the Original Publication -- Commentaries on the "Neuron Doctrine"--Cajal, Golgi, and Ariadne's Thread-Marina Bentivoglio -- Reflections on the Neuron Doctrine-Javier DeFelipe -- The Neuron Doctrine Revisited: A Personal Account-Sten Grillner -- Camillo Golgi, Foundations of the Neuron Doctrine, and the History of Neuroscience-Paolo Mazzarello -- Some Reflections on the Neuron Doctrine-Larry Swanson -- Back to Golgi? Neural Networks as a New Paradigm for Brain Circuits-Rafael Yuste -- 1. Introduction -- 2. From the Beginnings to the Cell Theory -- 3. Do Nerve Cells Belong in the Cell Theory? -- 4. Nerve Cells or Nerve Nets? -- 5. KÖlliker Gives In -- 6. Support Builds for Networks -- 7. The Nerve Cell Studies of Freud -- 8. The Revolutionary Method of Golgi -- 9. A Neuron Theory Begins to Take Form: His, Forel, Nansen -- 10. Ramón y Cajal: The Shock of Recognition -- 11. The Early Discoveries of Cajal -- 12. The Laws of Cajal -- 13. Joining the Mainstream -- 14. The Neuron Doctrine -- 15. The Law of Dynamic Polarization -- 16. Controversy -- 17. The Synapse and the Growth Cone -- 18. Forging a Consensus -- 19. Confrontation in Stockholm -- 20. Modern Revisions of the Neuron Doctrine -- References -- Index.

Foundations of the Neuron Doctrine

This is a thorough revision of the standard text on local circuits in the different regions of the brain. In this fifth edition, the results of the mouse and human genome projects are incorporated for the first time. Also for the first time, the reader is oriented to supporting neuroscience databases. Among the new advances covered are 2-photon confocal laser microscopy of dendrites and dendritic spines, biochemical analyses, and dual patch and multielectrode recordings, applied together with an increasing range of behavioral and gene-targeting methods.

The Synaptic Organization of the Brain

Sten Grillner

In order to focus on principles, each chapter in this work is brief, organized around 1-3 wiring diagrams of the key circuits, with several pages of text that distil the functional significance of each microcircuit

Handbook of Brain Microcircuits

In his new book, Gordon M. Shepherd expands on the startling discovery that the brain creates the taste of wine. This approach to understanding wine's sensory experience draws on findings in neuroscience, biomechanics, human physiology, and traditional enology. Shepherd shows, just as he did in Neurogastronomy: How the Brain Creates Flavor and Why It Matters, that creating the taste of wine engages more of the brain than does any other human behavior. He clearly illustrates the scientific underpinnings of this process, along the way enhancing our enjoyment of wine. Neuroenology is the first book on wine tasting by a neuroscientist. It begins with the movements of wine through the mouth and then consults recent research to explain the function of retronasal smell and its extraordinary power in creating wine taste. Shepherd comprehensively explains how the specific sensory pathways in the cerebral cortex create the memory of wine and how language is used to identify and imprint wine characteristics. Intended for a broad audience of readers—from amateur wine drinkers to sommeliers, from casual foodies to seasoned chefs—Neuroenology shows how the emotion of pleasure is the final judge of the wine experience. It includes practical tips for a scientifically informed wine tasting and closes with a delightful account of Shepherd's experience tasting classic Bordeaux vintages with French winemaker Jean-Claude Berrouet of the Chateau Petrus and Dominus Estate.

Gordon M. Shepherd

About

Books

Join the club