Hans Selye

A physician explains the general-adaptation-syndrome concept of stress and discusses the laboratory research that led to its evolution

The Stress of Life

Completely revised, expanded, and updated to reflect two decades of new research, this classic book on stress by the man who formulated the entire theoretical concept is unquestionably the definitive gerneral book on the subject. Defined ed as the rate of wear and tear caused by life, stress is a new concept of mental and physical illness. Dr. Selye here explains how to overcome the harmful effects of stress and how to use stress to your own advantage. He explores both biochemical and environmental facets of stress, stress and interpersonal relations, and offers readers a better understanding of their own bodies. This is also a dependable personal guide that tells you how to combat both physical and mental stress of everyday life, and how your bodily changes can help you adapt to a wide variety of situations. Unquestionably one of the great pioneers of medicine, Dr. Hans Selye, with his famous and revolutionary concept of stress, opened countless new avenues of medical treatment.

7 If so, the individual members of each class thus identified could then be subjected to a more profound pharmacokinetic analysis. In other words, we had to determine first which hormone protects against which drug, before we could explore how it did this. We had to know first that a hormone has adaptive value before we could ask whether this is due to a syntoxic or a catatoxic mechanism. Such observations, as the fact that an indomethacin-induced intestinal ulcer can be prevented by ethylestrenol, orthat cortisol aggravates certain infections, reveal nothing about how these hormones work; but only findings of this type can tell us where further research would be rewarding. Of course, scientists can rarely identify by direct observation the tbings that they are looking for; most of the time they have to be guided by indirect indices. The ebernist often first detects a compound, or even a particular functional group in its molecule, by inference from a color reaction, a revealing X-ray diffraction pattern or the formation of a characteristic precipitate. The physician must first suspect the presence of a microbe through certain clinical signs and symptoms before he can verify his diagnosis by looking for a particular organism. It is perhaps not too daring to hope that in our first efforts to clarify the role of hormones in resistance, simple, directly visible indicators might also serve us best.

Part 1 and Part 2

Hormones and Resistance

George Ember

Symbolic Shorthand System (SSS) for Physiology and Medicine

The Mast Cells

Textbook of Endocrinology

A Treatise Based on the Concepts of the General-adaptation-syndrome and the Diseases of Adaptation

The Physiology and Pathology of Exposure to Stress

Annual report on stress

The Physiology and Pathology of Exposure to Stress; a Treatise Based on the Concepts of the General-adaptation-syndrome and the Diseases of Adaptation

Lebensregeln vom Entdecker d. Stress-Syndroms

Stress

Alexander Horava

Annual Report on Stress

Hans Selye

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