Henry J. McQuay

Eija Kalso

Contains papers from the first international research symposium of the International Association for the Study of Pain, held in Helsinki, Finland, Fall 1998. Focus is on opioid responsiveness to neuropathic pain. Papers are arranged in sections on function and dysfunction of opioid receptors, clinical pharmacology of opioids, understanding and improving opioid sensitivity, and opioid sensitivity of different chronic pain states. Specific topics include targeting of opioid receptors to presynaptic sites, route of opioid administration, phenotypic changes induced in dorsal root ganglion neurons by nerve injury, and opioids in headache. Kalso is currently affiliated with the Karolinska Institute in Sweden. IASP member price, $44.85. Annotation copyrighted by Book News, Inc., Portland, OR.

Opioid Sensitivity of Chronic Noncancer Pain

R. Andrew Moore

This easy to read pocketbook, written by world leaders in the field of evidence-based pain treatments, acts as a simple guide for people who wish to make sense of evidence in a healthcare setting and who want to avoid being misled by faulty evidence.It provides practical guidelines on how to make sense of and interpret the evidence that is available, with information on how to avoid straying beyond evidence into conjecture, supposition, and wishful thinking. It covers size, trial design, harm as well as benefit, and health economics and management evidence. 'Bandolier's Little Book of Making Sense of the Medical Evidence' has not been written as a comprehensive manual for those who want to do a systematic review or a meta-analysis, noras a statistical or methodological textbook for students. Its origins lie in lectures for medical students, healthcare professionals from a variety of settings, and journalists. This book is a summary of the tools that Bandolier uses to assess evidence, to be able to distinguish good evidence frombad. It will be an invaluable resource for university course and GP tutors, family doctors, hospital consultants involved in research, pharmacists, and anyone interested in evidence-based health care.

Henry J. McQuay

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