Jun Zhang

Yuanwei Liu

Xingqin Lin

Joongheon Kim

This book begins with a historical overview of the evolution of mobile technologies and addresses two key questions: why do we need 6G? and what will 6G be? The remaining chapters of this book are organized into three parts: Part I covers the foundation of an end-to-end 6G system by presenting 6G vision, driving forces, key performance indicators, and societal requirements on digital inclusion, sustainability, and intelligence. Part II presents key radio technology components for the 6G communications to deliver extreme performance, including new radio access technologies at high frequencies, joint communications and sensing, AI-driven air interface, among others. Part III describes key enablers for intelligent 6G networking, including network disaggregation, edge computing, data-driven management and orchestration, network security and trustworthiness, among others. This book is relevant to researchers, professionals, and academics working in 5G/6G and beyond.

Fundamentals of 6G Communications and Networking

Oscar Arrieta

Jarushka Naidoo

Optimizing Outcomes and Addressing Adversities of Immunotherapy in Lung Cancer

Zhi Jian Wang

Shu Ren Zhu

Xiao Ming Meng

The present book includes selected papers from the 2012 International Conference on Information Technology and Management Innovation (ICITMI 2012), held in Guangzhou, from 10 to 11 November 2012. Volume is indexed by Thomson Reuters CPCI-S (WoS). These selected papers reflect the interdisciplinary nature of the conference and the diversity of topics is an important feature of this conference, enabling an overall perception of several important scientific and technological trends.

Information Technology Applications in Industry

Gai Fei Peng

Ting Yu Hao

Fa Guang Leng

Collection of selected, peer reviewed papers from the 10th International Symposium on High Performance Concrete  Innovation & Utilization (HPC 2014), September 16-18, 2014, Beijing, China. The 87 papers are grouped as follows: Chapter 1: High-Performance and Ultra-High Performance Concrete, Chapter 2: Concrete Durability and Mechanical Properties, Chapter 3: Fire Resistance, Chapter 4: Concrete Sustainability, Recycling and Utilization, Chapter 5: Mix Proportion Design and Hydration, Chapter 6: Self-Compacting Concrete, Chapter 7: Special Raw Materials, Concrete Composites and Additives, Chapter 8: Structural Performance and Modeling, Chapter 9: Testing Methods, Evaluation and Quality

High Performance Concrete  Innovation & Utilization

Yao Xiao

Mengqi Zhao 

Xiaoling Wang

Jia Yu

Construction duration and schedule robustness are of great importance to ensure ecient construction. However, the current literature has neglected the importance of schedule robustness. Relatively little attention has been paid to schedule robustness via deviation of an activity’s starting time, which does not consider schedule robustness via structural deviation caused by the logical relationships among activities. This leads to a possibility of deviation between the planned schedule and the actual situation.

Optimization of Construction Duration and Schedule Robustness Based on Hybrid GreyWolf Optimizer with Sine Cosine Algorithm

Ji-Huan He

Yuxi Fu

The 2004 International Symposium on Computational and Information Sciences (CIS 2004) aimed at bringing researchers in the area of computational and - formation sciences together to exchange new ideas and to explore new ground. The goal of the conference was to push the application of modern computing technologies to science, engineering, and information technologies to a new level of sophistication and understanding. Theinitialideatoorganizesuchaconferencewithafocusoncomputationand applicationswasoriginatedbyDr.JunZhang,duringhisvisittoChinainAugust 2003, in consultation with a few friends, including Dr. Jing Liu at the Chinese Academy of Sciences, Dr. Jun-Hai Yong at Tsinghua University, Dr. Geng Yang at Nanjing University of Posts and Communications, and a few others. After severaldiscussionswithDr.Ji-HuanHe,itwasdecidedthatDonghuaUniversity would host CIS 2004. CIS 2004 attempted to distinguish itself from other conferences in its - phasis on participation rather than publication. A submitted paper was only reviewed with the explicit understanding that, if accepted, at least one of the authors would attend and present the paper at the conference. It is our - lief that attending conferences is an important part of one’s academic career, through which academic networks can be built that may bene?t one’s academic life in the long run. We also made every e?ort to support graduate students in attending CIS 2004. In addition to set reduced registration fees for full-time graduate students, we awarded up to three prizes for to the Best Student Papers at CIS 2004. Students whose papers were selected for awards were given cash prizes, plus a waiver of registration fees.

First International Symposium, CIS 2004, Shanghai, China, December 16-18, 2004, Proceedings

Computational and Information Science

Hong Zhou

This book systematically reviews the development of social policy since the establishment of the People’s Republic of China. As such, it begins by investigating the establishment of the Insurance System in the early period, then moves on to the planned economy period, the Cultural Revolution period, and the Reform and Opening Up period, characterized by efforts to adapt to a market economy. For each period, the book examines the effect of the economic system, the mode of production and forms of employment for social policy design, so as to clarify the developing context of Chinese social policy, and to help readers grasp the legal aspects of social policy development and the main problems China faces in its present economic developmental stage.

A Concise History of Social Security Transformation in Modern China

Towards a Society with Social Protection for All

Michael V. Knopp

This book is a guide to new and emerging PET technology, instrumentation, and its place in clinical practice. PET technology is currently moving from the conventional photomultiplier tube (PMT) detector based PET to the new generation, solid state light sensor detector. This is a technological leap and holds significant implications for the use of PET imaging. This book introduces and describes the emerging and new generation of PET instrumentations and technologies across manufactures, focusing on solid-state PET detector designs, system characteristics, and clinical practices as well as future advanced Time-of-Flight (TOF) PET technologies. Organized into three sections, the basics of PET imaging; solid state digital PET instrumentation, technology, and clinical practice; and a look to the future of PET imaging, chapters present a full picture of PET imaging, where we are and where we will be. Nuclear medicine physicians, physicists, and technologists can use this book to better understand future PET systems, novel PET technologies, and potential game changes of clinical PET practice.

The Latest in Instrumentation, Technology, and Clinical Practice

Advances in PET

In this book, Dr. Jun Zhang rebuts the widely-held view that Chinese economic growth is unsustainable due to low consumption and a reliance on exports and enormous fixed-asset investments. Though many believe this “structural imbalance” of the Chinese economy will become a serious problem in the long run, Zhang holds a bullish long-term outlook owing to China's long-term economic development. For Zhang, China’s structural problems are greatly exaggerated and certain structures, such as regional governing entities, ensure that China will not face the same economic issues that Japan encountered. Through regional competition, regional governments will persevere; Zhang predicts that China will overtake the US as a superpower. Zhang concludes by acknowledging the real dangers facing China’s economy, and offering advice on the reforms needed to ensure continued growth.

End of Hyper Growth in China?

In Driving toward Modernity, Jun Zhang ethnographically explores the entanglement between the rise of the automotive regime and emergence of the middle class in South China. Focusing on the Pearl River Delta, one of the nation's wealthiest regions, Zhang shows how private cars have shaped everyday middle-class sociality, solidarity, and subjectivity, and how the automotive regime has helped make the new middle classes of the PRC. By carefully analyzing how physical and social mobility intertwines, Driving toward Modernity paints a nuanced picture of modern Chinese life, comprising the continuity and rupture as well as the structure and agency of China's great transformation.

Cars and the Lives of the Middle Class in Contemporary China

Driving toward Modernity

Xiaofeng Chen

Xinyi Huang

This book constitutes the proceedings of the Second International Conference on Machine Learning for Cyber Security, ML4CS 2019, held in Xi’an, China in September 2019. The 23 revised full papers and 3 short papers presented were carefully reviewed and selected from 70 submissions. The papers detail all aspects of machine learning in network infrastructure security, in network security detections and in application software security.

Second International Conference, ML4CS 2019, Xi’an, China, September 19-21, 2019, Proceedings

Machine Learning for Cyber Security

Alzheimer’s disease (AD) is characterized by two main protein aggregate hallmarks in the brain: extracellular deposition of the amyloid-? (A?) in senile plaques and intracellular neurofibrillary tangles (NFTs) consisting of hyperphosphorylated tau protein. The past decade has seen great progress in the development of imaging probes for the non-invasive detection of A? and tau aggregates. Here positron emission tomography (PET), single-photon emission computed tomography (SPECT) and magnetic resonance imaging (MRI), are highly promising technologies for clinical diagnostics. However, as a research tool, optical imaging is superior because it is real-time, sensitive, inexpensive, not radioactive and that it in particular affords high-resolution studies both in vitro and in vivo. Fluorescent probes are especially useful for designing novel binding scaffolds for structure investigations of protein aggregates. This thesis describes design, synthesis and evaluation of a series of fluorescent probes for detection of amyloid fibrils, especially A? or tau aggregates in vitro. Firstly, trans-stilbenoid vinylbenzene-1,2-diol with benzene, naphthalene, anthracene, and pyrene are investigated with respect to their photophysical properties free in solution and when bound to amyloid fibrils, including time-resolved fluorescence measurements. It is noted that the extended conjugated systems retained the amyloid targeting properties of the probes and both the anthracene and pyrene moieties extensively enhanced the fluorescence intensity and prolonged lifetimes. Secondly, the synthesis of two molecules, Py1SA and Py2SA, based on pyrene linked to salicylic acid via a trans-stilbene C = C bond is presented. The compounds show strikingly different emission spectra when bound to preformed A?1-42 fibrils as well as to fibrils from four other distinct proteins. Additionally, excited state intramolecular proton transfer (ESIPT) coupled-charge transfer (ICT) is observed for the anionic form of the probes in polar solvents. This is likely the reason for the spectral differences of the probes when bound to amyloid fibrils. Moreover, the synthesis of a further development of the Congo red analogue X-34 [2,5-bis(4’-hydroxy-3’-carboxy-styryl) benzene] by rational design and synthesis is described. Full photophysical characterization was performed, including recording absorbance and fluorescence spectra, Stokes shift, quantum yield and fluorescence lifetimes. All ligands displayed high affinity towards recombinant amyloid fibrils of A?1-42 and tau as well as selectivity towards the corresponding disease-associated protein aggregates in human post mortem AD tissue. Lastly, the synthesis of a set of 2,1,3-benzothiadiazole (BTD)-based ligands with different conjugated spacers and variable patterns of OH substitutions of bis-styryl-BTD prototypes were developed. A? binding affinities (A?1-42 and A?1-40 fibrils) and the specificity towards A? plaques of all ligands were determined. These findings extend the structure to activity relationships of BTD-based ligands for A? fibril binding. Throughout the studies in this dissertation, new interesting properties of small molecule fluorescence probes have been discovered and analyzed. This knowledge should facilitate the development of noninvasive probes for early detection of Alzheimer's disease and to distinguish different A? fibril polymorphs.

Jun Zhang

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