Professor of Resiratory Medicine Kian Fan Chung

Fan Chung Graham

Fan Chung

Fan R. K. Chung

Linyuan Lu

Kian Fan Chung

Through examples of large complex graphs in realistic networks, research in graph theory has been forging ahead into exciting new directions. Graph theory has emerged as a primary tool for detecting numerous hidden structures in various information networks, including Internet graphs, social networks, biological networks, or, more generally, any graph representing relations in massive data sets. How will we explain from first principles the universal and ubiquitous coherence in the structure of these realistic but complex networks? In order to analyze these large sparse graphs, we use combinatorial, probabilistic, and spectral methods, as well as new and improved tools to analyze these networks. The examples of these networks have led us to focus on new, general, and powerful ways to look at graph theory.The book, based on lectures given at the CBMS Workshop on the Combinatorics of Large Sparse Graphs, presents new perspectives in graph theory and helps to contribute to a sound scientific foundation for our understanding of discrete networks that permeate this information age.

Complex Graphs and Networks

John G. Widdicombe

Homer A. Boushey

Cough is the most familiar symptom of respiratory disease, and a problem which general practitioners must deal with on a daily basis. This timely volume draws together a wealth of recent research into the mechanisms, pharmacology and therapies for cough, and places these in clinical context. The text incorporates guidelines on the most common causes of cough, discusses treatments and pitfalls in management, summarizes current research on physiology, pharmacology and treatment of cough, and gives practical advice on diagnosis and management issues for the clinician. Cough: Causes, Mechanisms and Therapy is the most comprehensive, up-to-date account of the subject. It will update clinical and basic medical scientists, and promote future research. Readers are encouraged to implement the clinical implications of the discussion into routine practice. This volume will appeal to all those involved in the treatment of respiratory disease, particularly those in hospital respiratory units, and will also be of use to interested general practitioners.

Causes, Mechanisms and Therapy

Cough

Elliot Israel

Peter G. Gibson

Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.

Severe Asthma

Kian Fan Chung

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