Klaus Linde

Karin Meissner

More invasive and impressive therapeutic rituals are generally believed to be more powerful interventions than less impressive ones. This chapter reviews and discusses evidence from randomized clinical trials and meta-analyses for such a differential effectiveness of placebo interventions. Evidence from clinical research that different types of placebo are regularly associated with different magnitudes of placebo effect is limited. However, one area where hints from a variety of sources are accumulating is sham acupuncture in the treatment of pain. Furthermore, there is preliminary evidence that sham surgery and ambiguous evidence that sham injections are associated with enhanced placebo effects on pain. Among the factors that may account for a greater effectiveness of such treatment procedures are the lively perceptual context of the procedures themselves, the attention and enhanced emotional support by healthcare providers, and the increased expectation and motivation of patients. A differential effectiveness of placebo control procedures in clinical trials would have important implications for clinical research.

Chapter 23. What are the Best Placebo Interventions for the Treatment of Pain?

Placebo and Pain

Claudia Witt

You want to conduct a CAM study but don’t know how? Problem solved – Clinical Research demonstrates all aspects of state-of-the-art study design in an understandable and practical way. You will get a comprehensive overview and instruction – step by step. The code in the book will give you 12 months of free online access to the content and illustrations of the book. This practical training book: systematically introduces the key aspects of study design and basic statistics. helps you to develop, plan and execute your research project. combines established theoretical approaches with practical skills applicable to your own clinical study. is a step-by-step tutorial for a complete clinical study, which is illustrated in three case studies. includes additional training exercises, featuring different study conditions and environments, that will help you to practice and test your knowledge. Clinical Research in Complementary and Integrative Medicine – the best way to understand clinical research and to plan and perform your own study! Free online access: After activating the code inside this book you get free online access to the content and the illustrations for 12 months.

Klaus Linde

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