Jian Yang

Hua Huang

Huchuan Lu

Yi Sun

Lihe Zhang

This book constitutes the proceedings of the 7th International Conference on Intelligence Science and Big Data Engineering, IScIDE 2017, held in Dalian, China, in September 2017.The 48 full papers and 14 short papers presented in this volume were carefully reviewed and selected from 121 submissions. They deal with statistics and learning; deep neural networks; faces and people; objects; classification and clustering; imaging; biomedical signal processing; and recommendation.

7th International Conference, IScIDE 2017, Dalian, China, September 22-23, 2017, Proceedings

Intelligence Science and Big Data Engineering

Xinjing Tang

Zhen Xi

Jyoti Chattopadhyaya

Nucleic Acids in Medicinal Chemistry and Chemical Biology An up-to-date and comprehensive exploration of nucleic acid medicinal chemistry and its applications In Nucleic Acids in Medicinal Chemistry and Chemical Biology: Drug Development and Clinical Applications, a team of distinguished researchers delivers a comprehensive overview of the chemistry and biology of nucleic acids and their therapeutic applications. The book emphasizes the latest research in the field, including new technologies like CRISPR that create novel possibilities to edit mutated genes at the genomic DNA level and to treat inherited diseases and cancers. The authors explore the application of modified nucleosides and nucleotides in medicinal chemistry, a variety of current topics on nucleic acid chemistry and biology, nucleic acid drugs used to treat disease, and more. They also probe new domains of pharmaceutical research, offering the reader a wealth of new drug discovery opportunities emerging in this dynamic field. Readers will also find: A thorough introduction to the basic terminology and knowledge of the field of nucleic acid medicinal chemistry Comprehensive explorations of the methods used to determine the development of nucleic acid drugs Practical discussions of new technologies, like CRISPR, nanotechnology-based delivery systems, synthetic biology, and DNA-encoded chemical libraries In-depth examinations of the latest, cutting-edge developments in nucleic acid medicinal chemistry Perfect for medicinal and nucleic acid chemists, Nucleic Acids in Medicinal Chemistry and Chemical Biology will also earn a place in the libraries of biochemists, chemical biologists, and pharmaceutical researchers.

Drug Development and Clinical Applications

Nucleic Acids in Medicinal Chemistry and Chemical Biology

Lihe Zhang

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