Luther W. Brady

Zbigniew Petrovich

Luc Baert

Current information on the etiology, diagnosis, and treatment of carcinomas of the kidney and testis, as well as several less common tumors of the genitourinary tract. Recent contributions in epidemiology and molecular genetics are discussed with a view to their importance for clinical practice, while novel approaches to the treatment of several important tumors are presented, with emphasis on multidisciplinary patient management. Numerous illustrations assist readers in obtaining a better understanding of the data presented.

Innovations in Management

Carcinoma of the Kidney and Testis, and Rare Urologic Malignancies

Concentrating on the diagnosis and treatment of carcinoma of the bladder, rather than the entire field of genitourinary oncology, this book discusses in depth all the important advances in molecular genetics of relevance to clinical practice. Progress in both imaging and non-imaging modalities from recent clinical trials is well documented and critically evaluated in a manner that will prove invaluable for practising urooncologists. Furthermore, the management of patients with superficial, muscle-invasive, and advanced disease is discussed, and new treatment results presented. Numerous illustrations and tables serve to assist in understanding the data presented.

Carcinoma of the Bladder

Carlos A. Perez

Edward C. Halperin

The thoroughly updated fifth edition of this landmark work has been extensively revised to better represent the rapidly changing field of radiation oncology and to provide an understanding of the many aspects of radiation oncology. This edition places greater emphasis on use of radiation treatment in palliative and supportive care as well as therapy.

Perez and Brady's Principles and Practice of Radiation Oncology

Jiade J. Lu

Radiation Oncology: An Evidence-Based Approach (ROEBA) is a reference book designed to enable radiation oncologists, including those in training, to make diagnostic and treatment decisions on the basis of the best available scientific evidence. Ease of use is ensured by a structured, reader-friendly format that offers rapid access to evidence-based recommendations. ROEBA’s orientation is entirely practical, in that the focus is solely on diagnostic/staging and treatment issues. Detailed diagnostic and therapeutic guidelines are provided for multidisciplinary cancer management as well as radiation therapy techniques. The evidence underlying each recommendation is clearly and concisely explained, and the strength of the recommendations and evidence is systemically graded. Furthermore, diagnostic and treatment algorithms are provided for the commonly diagnosed cancers. This ground-breaking text on radiation oncology is an essential tool for physicians in their daily clinical practice.

An Evidence-Based Approach

Radiation Oncology

Felipe A. Calvo

Manuel Santos

The development of the capacity to use electron beams at various energies stimulated the development of the new technology of intraoperative radiation therapy. The visual ization of the primary tumor, definition of the site to be irradiated, and knowledge of the size of tumor to be irradiated, including adequate margins for microscopic extent along with debulking of the tumor, have allowed intraoperative radiation therapy to be pur sued in a wide variety of disease processes. Not only is it possible to treat tumors that were highly resistant, but it is also possible to specifically localize the tumor with a mar gin adequate to encompass potential microscopic extensions and to choose the appro priate electron beam energy to treat the potential residual tumor and spare the adjacent normal structures. It is, furthermore, possible to treat patients with unresectable tumors. Central to this entire development is the fact that normal structures can be removed from the field of treatment. In the beginning, the emphasis was on single fractions of electron beam radiation without subsequent supplementation by external photon beam radiation therapy. How ever, more recently it has become necessary to use not only a single electron beam frac tion during the course of the operation, but to supplement it with external beam treat ment. The encouraging results obtained with intraoperative radiation therapy have led to clinical trials at a large number of institutions throughout the world.

Clinical Experiences and Results

Intraoperative Radiotherapy

David E. Wazer

Inside the Sixth Edition of this now-reference, you will discover encyclopedic coverage of topics ranging from basic science to sophisticated computer-based radiation therapy treatment planning and supportive care. The book's comprehensive scope and abundantly illustrated format provide you with better understanding of the natural history of cancer, the physical methods of radiation application, the effects of radiation on normal tissues, and the most judicious ways in which you can employ radiation therapy in patient care. Including epidemiology, pathology, diagnostic work-up, prognostic factors, treatment techniques, applications of surgery and chemotherapy, end results, and more. Increased emphasis on new approaches and technologies improve your understanding of three-dimensional treatment planning, intensity-modulated radiotherapy, combined modality therapy, and particle therapy. Digital version includes the complete text, index-based search, note sharing, regular content updates integrated into the text, and much more.

Perez & Brady's Principles and Practice of Radiation Oncology

K. S. Clifford Chao

Designed for rapid, on-the-spot consultation, this handy manual presents the most essential information that is immediately required in the daily clinical practice of radiation oncology. The first 12 chapters succinctly review concepts that are crucial in treatment planning and patient management. The remaining 52 chapters describe treatment regimens for all cancer sites and tumor types.This revised, updated Second Edition reflects the past three years' many improvements in radiation treatment of malignancies. A new chapter covers intensity modulated radiation therapy (IMRT). The book contains more than 300 practical illustrations, including full-color in the chapters on IMRT and 3-D physics and treatment planning.

Management Decisions

Michael L. J. Apuzzo

Michael Bamberg

The American Cancer Society anticipates that 16,500 patients will be diagnosed with primary malignant tumors of the central nervous system in 2000, with about 200,000 individuals presenting with brain metastases. The advances in the treatment of solid tumors have contributed significantly to the major increase in metastatic cancers to the brain. Of the primary malignant tumors of the brain, more than 50% are high-grade gliomas; the incidence has been increasing among older patients over the past decade. Major developments in new technologies in the treatment of primary brain tumors as well as metastatic disease are covered in depth. Even though management is difficult, advances are being made. This book is a concerted effort to present data regarding basic science research efforts alongside their translation into clinical practice using combined, integrated multimodal programs of treatment. Progress has been made, but innovatice approaches need to be pursued.

Combined Modality Therapy of Central Nervous System Tumors

Klaus-Rüdiger Trott

Michael Heinrich Seegenschmiedt

Hans-Bruno Makoski

This volume discusses the background and various clinical applications of radiation therapy in the treatment of non-malignant diseases. It documents the radiobiological and physical principles of treatment and the rationale underlying the use of radiotherapy for various disorders of the CNS, head and neck, eye, skin and soft tissues, bone and joints, and vascular system. In so doing, it draws attention to and elucidates the scope for application of radiotherapy beyond the treatment of malignancies. Both the risks and the benefits of such treatment are fully considered, the former ranging from minor clinical problems to life-threatening diseases.

Luther W. Brady

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