Tariq Aftab

M. Naeem

M. Masroor A. Khan

This book studies the production of indole alkaloids in the important medicinal plant Catharanthus roseus (L.) G. Don, commonly known as periwinkle. The anticancer alkaloids, viz. vinblastine and vincristine, are mainly present in the leaves of C. roseus and inhibit the growth of cancer cells by hindering the formation of mitotic apparatus during cell division. Further, vinblastine helps increase the chance of surviving childhood leukemia while vincristine is used to treat Hodgkin’s disease. Great efforts have been made to produce these alkaloids at a large scale by the culture of plant cells. In view of this worldwide demand for commercial use, this book explores how to maximize the production of anticancer alkaloids from C. roseus. This reference book will be helpful for research students, teachers, ethnobotanists, pharmacologists and herbal growers who have a strong interest in this anticancer medicinal plant of paramount importance.

Current Research and Future Prospects

Catharanthus roseus

Jorge F.S. Ferreira

Artemisinin, a sesquiterpene lactone originally extracted from the medicinal plant Artemisia annua L., is an effective antimalarial agent, particularly for multi-drug resistant and cerebral malaria. However, the concentration of artemisinin in the plant is very low. Because the chemical synthesis of artemisinin is complicated and not economically feasible in view of the poor yield of the drug, the intact plant remains the only viable source of artemisinin production. Therefore, it is necessary to increase the concentration of artemisinin in A. annua to reduce the cost of artemisinin based antimalarial drugs. Plant scientists have focused their efforts on A. annua for a higher artemisinin crop yield. With the present volume, we are bringing together the research which is being done on this plant throughout the world and future possibilities for scientists and researchers who want to work on it.

Artemisia annua - Pharmacology and Biotechnology

Sarvajeet Singh Gill

Abid Ali Ansari

Juan Francisco Jimenez Bremont

This volume ‘Agrochemicals in Soil and Environment: Impacts and Remediation’ is a comprehensive collection of important literature on agrochemical contamination. The main focus of this book is to point out undesirable changes in biological, physical and chemical characteristics of agricultural soils and its impacts on global agricultural crop productivity. Soil is one of the important resources of basic needs for our sustenance but due to various anthropogenic activities like urbanization and industrialization, the soil is losing its basic quality characteristics. Soil microorganisms, water holding capacity, minerals, salts and nutrients are under the direct threat due to agrochemicals therefore, agricultural sector is facing a serious challenge. Lack of proper knowledge and luxurious applications of agrochemicals resulting into degradation and deterioration of soil quality, loss of soil and crop productivity and threatening the food security. Therefore, it is imperative to develop indices, indicators and soil parameters for the monitoring and impact assessment of agricultural contaminants. Further, biotic and abiotic stresses and their tolerance mechanisms in plants in relation to the soil contaminants such as toxic pollutants, heavy metals, inorganic and organic matters, variety of pesticides, insecticides, herbicides, agricultural runoffs and solid wastes, and chemical fertilizers are also highlighted in this volume. This book also discusses causes of reduced agriculture productivity and suggests sustainable measures such as plant-based technologies, bioremediation and nanotechnology, that can be used to overcome the crop losses. The book is interest to research students, teachers, agricultural scientists, agronomists, environmentalists as well as policy makers.

Impacts and Remediation

Agrochemicals in Soil and Environment

Anca Macovei

Hazardous and Trace Materials in Soil and Plants: Sources, Effects and Management explores the latest advancements in reducing, avoiding and eliminating soil contaminants that challenge the health and safety of agricultural plants. With a focus on minimizing the production of those hazardous substances, controlling their distribution and ensuring safe utilization, the book explores each contributing area and provides insights toward improved, sustainable and secure production. This is an excellent reference resource on both current research and future directions from laboratory research to field applications. The combined impacts of climate change and industrialization have led to increased and diversified threats to the health of the soil in which our food crops are grown, as well as in the plants themselves. This dual-hazard scenario is increasingly recognized as a threat to not just the environment, but to global food security as agricultural soils contaminated with pollutants alter plant metabolism, thus resulting in reduced crop quality and production quantity. Addresses the challenges of mitigating toxic substances in plants, including agricultural crops Presents current status and future prospects for managing biotic and abiotic environmental stress factors through plant stress tolerance mechanisms Includes chapters that address both biotic and abiotic stresses, agricultural and environmental science, toxicology, biotechnology, nanotechnology, and molecular studies Integrates insights and developments between environmental and plant science

Sources, Effects, and Management

Hazardous and Trace Materials in Soil and Plants

This contributed volume brings together an inclusive collection of information about the medicinal crop fenugreek (Trigonella foenum-graecum). Fenugreek is one of the medicinal plants important in the management of diabetes and contributes greatly in the alternative systems of medicine. These beneficial properties of fenugreek are covered in here. Further, this book explores the agronomy, biotechnology, genomics and biochemistry aspects of the crop. This book is of interest to teachers, researchers, agronomists and biochemists. Also, the book serves as additional reading material for graduate students of agriculture and pharmacology. National and international agricultural scientists, policy makers will also find this to be a useful read.

Biology and Applications

Fenugreek

This comprehensive volume covers recent studies into agricultural problems caused by soil and water contamination. Considering the importance of agricultural crops to human health, the editors have focused on chapters detailing the negative impact of heavy metals, excessive chemical fertilizer use, nutrients, pesticides, herbicides, insecticides, agricultural wastes and toxic pollutants, among others, on agricultural soil and crops. In addition, the chapters offer solutions to these negative impacts through various scientific approaches, including using biotechnology, nanotechnology, nutrient management strategies, biofertilizers, as well as potent PGRs and elicitors. This book serves as a key source of information on scientific and engineered approaches and challenges for the bioremediation of agricultural contamination worldwide. This book should be helpful for research students, teachers, agriculturalists, agronomists, botanists, and plant growers, as well as in the fields of agriculture, agronomy, plant science, plant biology, and biotechnology, among others. It serves as an excellent reference on the current research and future directions of contaminants in agriculture from laboratory research to field application.

Sources, Impacts and Management

Contaminants in Agriculture

Artemisia annua is a well-known medicinal plant that has been utilized for a number of purposes, including malaria, for centuries. This is the first comprehensive book to cover the importance of Artemisia annua in the global health crisis and in the treatment against diseases. A component and extract, artemisinin, is the source of other derivatives which are also suitable for pharmaceutical use. The present demand for artemisinin far outpaces its supply. Researchers are working globally towards improving artemisinin content in the plant by various means. Artemisia annua: Prospects, Applications and Therapeutic Uses highlights the different approaches, including ‘omics', that are being used in current research on this immensely important medicinal plant. Providing comprehensive coverage of the agricultural and pharmaceutical uses of this plant, Artemisia annua will be essential reading for botanists, plant scientists, herbalists, pharmacognosists, pharmacologists and natural product chemists.

M. Naeem

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