Mary McMahon

This detailed book describes some of the most recent advances and up-to-date methodologies to detect, quantify, analyze, and elucidate the biological function of different types of RNA modifications. Importantly, the methodologies and tools described herein can be applied to a wide variety of organisms and can be used to address biological and clinical questions. Beginning with a section on bioinformatics tools, the collection continues with sections on detecting RNA modifications using Nanopore direct RNA sequencing, next-generation sequencing approaches, qPCR- and molecular biology-based methods, mass spectrometry- and NMR-based methods, as well as approaches to assess kinetics, determinants, and functions of RNA modifications. Written for the highly successful Methods in Molecular Biology series style, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, RNA Modifications: Methods and Protocols serves as an ideal guide for those working directly in the fields of epitranscriptomics and post-transcriptional gene regulation, as well as for scientists and clinicians interested in bioinformatic tools to study RNA modifications and techniques to dissect their roles in physiology and disease. Chapter 20 is available open access under a CC BY 4.0 license.

Methods and Protocols

RNA Modifications

Nancy Arthur

In response to the complexities of social change that have become evident in the 21st century, there is a need for innovation in career theory that takes into account new perspectives and the fluctuating contexts of people’s lives. Contemporary Theories of Career Development: International Perspectives brings together the contributions of theorists from around the globe whose work represents current, cutting-edge international approaches to career development theory. Emphasizing the new perspectives that are needed for this field to be relevant in a contemporary era, this book considers the cultural applications of theory in a diverse range of populations. Structured in three parts with chapters written by internationally renowned leaders in the field, this collection features a critical examination of the current history of the field; thirteen theory chapters, each enhanced by a case study; and a final chapter that draws the previous chapters together through key themes, broadening the reader’s knowledge of theoretical perspectives and their interrelations. Each theory chapter author comments on and critiques his or her own theory, inviting readers to engage with these theories at both a practical and theoretical level through the case studies. Detailed, with reader-friendly descriptions and supplemented by international research, case examples, and discussion questions, Contemporary Theories of Career Development: International Perspectives is the ideal reference work for students studying the topic as well as a stimulus for researchers and practitioners looking to implement the theories in their work.

International Perspectives

Contemporary Theories of Career Development

Mystery on the Orient Express

Mark Watson

Career Assessment: Qualitative Approaches will assume a seminal place in the field of career development as the first book to focus solely on qualitative approaches to career assessment. This book represents a timely and important contribution to career development as it seeks to meet the needs of increasingly diverse client groups. Part 1, Foundations strongly positions qualitative career assessment in its historical, philosophical, theoretical and research contexts. The book is innovative by considering qualitative career assessment through the lens of learning. Part 2, Instruments, presents the first collation of chapters on a comprehensive range of qualitative career assessment instruments and processes written to a standard format to enable readers to compare, contrast and evaluate approaches. Part 3, Using quantitative career assessment qualitatively, mitigates against depicting an unnecessary divide in the field between quantitative and qualitative career assessment by considering their complementarities. Part 4, Diverse Contexts, considers qualitative approaches to career assessment in contexts other than able western, middle class settings. Part 5, Future Directions, reflects on the chapters and poses suggestions for the future. With high profile authors from nine different countries, the book represents a truly international contribution to the field of career development. In its focus on qualitative career assessment, this book holds a unique position as the only such text and will therefore assume an important place in the libraries of researchers, academics, and career practitioners.

Qualitative Approaches

Career Assessment

Career Exploration and Development in Childhood presents chapters from leading figures in the field of childhood career exploration and development. The first substantive edited collection of its kind, this book makes an important contribution to our understanding of children’s career development. It provides cutting-edge theory, research and practice for understanding and fostering career exploration and development during childhood, across a wide spectrum of international settings. Divided into five sections that reflect the authors’ perspectives on critical aspects of children’s career development, chapters include relevant research, as well as the practical application of concepts, issues and strategies for career interventions with children. The book includes sequential sections on theory, research, contextual influences, assessment, and the facilitation of career exploration and development. Perspectives from both developed and developing world contexts consider traditional approaches to career education, as well as career development learning in childhood. The collaborations evident in the chapter authorship reflect the significant internationalisation of the field of child career development. The book synthesises key issues and presents innovative recommendations that will not only enhance our understanding of children’s career development, but will set the agenda for the future of the field. It will be of key interest to researchers, academics and postgraduate students in the fields of career development, career guidance, education, childhood, child development and counselling.

Perspectives from theory, practice and research

Career Exploration and Development in Childhood

Wendy Patton

This fourth edition of the book attests to the Systems Theory Framework’s contemporary relevance. It introduces systems theory and the STF, overviews extant career theory, describes the STF’s applications, and highlights the STF’s contributions and future directions.

Mary McMahon

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