Michel Goldberg

Pamela Den Besten

This book addresses the structural and biological properties of dental and peridental tissue structures and covers their mineralization process. The book contains a description of dentines, cementum, enamel and bone, including collagens, as well as non-collagenous proteins (SIBLINGs, SLRPs, GAGs, PGs, lipids, and MMPs). The mechanisms of mineralization are described in detail and the book is focused on matrix vesicles, collagen mineralization and the role of non-collagenous extracellular matrix components either as promoters or inhibitors of mineralization. In addition, the matrix components (non-collagenous) of enamel (amelogenin, ameloblastin, enamelin, MMP4, MMP20 and other proteases) are reviewed and their respective roles in dental tissues biomineralizations and tissue turnover are discussed. Additionally, environmental factors involved in enamel / dentin defects are adressed. With state-of-the-art contributions from experts in the respective domains, the book is a useful introduction to the field for junior scientists, interested in dental and peridental tissue biomineralization. It is also an interesting read for advanced scientists and clinicians working in dental research, giving them a broader view of the topic beyond their area of specialization. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.

Extracellular Matrix Biomineralization of Dental Tissue Structures

​This book thoroughly explains the biological background of dental caries and the formation of carious lesions, providing the reader with a sound basis for understanding the role and effectiveness of different therapeutic and preventive measures. Detailed information is presented on pathogenesis, ultrastructure, and diagnosis. All aspects of the carious process are covered, including development of the initial carious lesion limited to the enamel, evolution of the enamel carious lesion toward a dentin carious lesion, superficial and deep dentin lesions, and cervical erosions. Strategies for prevention and dental tissue regeneration are elaborated and both conventional therapies and minimally invasive and non-invasive treatment approaches are discussed. A separate section is devoted to dental fluorosis and the use of fluoridation and remineralisation agents. This scientifically focused and clinically relevant book, written by acknowledged experts in the field, will appeal to dentists seeking to extend their knowledge as well as to researchers, dental students, and other dental professionals.

From Pathogenesis to Prevention and Therapy

Understanding Dental Caries

"This volume is the 1st in a series of Ebooks that bridges the gap between advances in science and clinical practice in odontology. Recent advances in biology, materials science and tissue engineering are increasingly viewed as being of enormous clinical p"

Amelogenins: Multifaceted Proteins for Dental and Bone Formation and Repair

The former French-Jewish international banker recounts his search for--and confrontation with--his father's Nazi killer, his itinerary--which took him to Entebbe and beyond, and his realization of his true identity

Michel Goldberg

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