Nourollah Ahmadi

Jérôme Bartholomé

This volume explores the conceptual framework and the practical issues related to genomic prediction of complex traits in human medicine and in animal and plant breeding. The book is organized into five parts. Part One reminds molecular genetics approaches intending to predict phenotypic variations. Part Two presents the principles of genomic prediction of complex traits, and reviews factors that affect its reliability. Part Three describes genomic prediction methods, including machine-learning approaches, accounting for different degree of biological complexity, and reviews the associated computer-packages. Part Four reports on emerging trends such as phenomic prediction and incorporation into genomic prediction models of “omics” data and crop growth models. Part Five is dedicated to lessons learned from cases studies in the fields of human health and animal and plant breeding, and to methods for analysis of the economic effectiveness of genomic prediction. Written in the highly successful Methods in Molecular Biology series format, the book provides theoretical bases and practical guidelines for an informed decision making of practitioners and identifies pertinent routes for further methodological researches. Cutting-edge and thorough, Complex Trait Predictions: Methods and Protocols is a valuable resource for scientists and researchers who are interested in learning more about this important and developing field. Chapters 3, 9, 13, 14, and 21 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Methods and Protocols

Genomic Prediction of Complex Traits

Joanna M. Cross

Chiarina Darrah

Nnadozie Oraguzie

Aleksandra Skirycz

Natural diversity has been extensively used to understand plant biology and improve crops. However, studies were commonly based on visual phenotypes or on a few measurable parameters. Nowadays, a large number of parameters can be measured thanks to next generation sequencing, metabolomics, proteomics, and transcriptomics thus providing an unprecedented resolution in the detection of natural diversity. This enhanced resolution offers new possibilities in terms of understanding plant biology. Technology advances also contribute to a better assessment of the biodiversity loss currently taking place. Hence, the topic presents an overview on efforts for maintaining biological diversity in crops, on possibilities offered by recent technologies in the assessment of natural variation, and ends with examples of the diversity found even at the cellular level.

Natural Diversity in the New Millennium

Abdulai Jalloh

Marco C S Wopereis

David E Johnson

Eric Tollens

At a time when Africa's food security stands threatened, Realizing Africa's Rice Promise provides a comprehensive overview of state-of-the-art research and recommendations for dealing with future challenges. With contributions from the key scientists working on rice in Africa, this volume addresses policy, genetic diversity and improvement, sustainable productivity enhancement, innovations and value chains. The book is useful for researchers, policy makers, agricultural ministries, donors, regional and sub-regional organizations, non-governmental development organizations and universities.

Realizing Africa's Rice Promise

Nourollah Ahmadi

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