O. Hockwin

W.B. Rathbun

Volume in Honour of Prof. John E. Harris, Ph. D., M. D.

Progress in Anterior Eye Segment Research and Practice

F. Bandello

D.H. Sliney

M. Kojima

N. Takahashi

Understanding cataract risk factors is a vital topic in preventative medicine and offers hope to the multitude of people in the world who cannot be aided by an intraocular lens implantation. In the multifaceted process of cataract development ultraviolet radiation is one of the important risk factors. This publication focuses on clinical studies, epidemiologic data as well as experimental approaches to ultraviolet radiation and its effects on the lens. Further articles discuss the cataract epidemiology and the biochemistry of the lens. In addition lens research in the 20th century is evaluated with regard to methods and results. The book is dedicated to Professor K. Sasaki from the University of Ishikawa (Japan) and his research over the last twenty years. Ophthalmologists in practice as well as those involved in lens and cataract research or interested in the mechanisms and the pathogenesis of lens opacification in old age will find a wealth of information in this volume. Likewise, it will be essential to physicians working in public health services, environmental medicine, and those concerned with eye damage caused by radiation.

In Honour of Professor Kazuyuki Sasaki

Progress in Lens and Cataract Research

Keith Green

Ramesh C. Tripathi

I. Weisse

On behalf of the editorial board and the organizing committee of the 4th congress of the International Society of Ocular Toxicology (I SOT), held in AnnecyNeyrier du Lac, France, October 9 -13, 1994, we are pleased to present to the ocular toxicology community this indexed volume of our congress proceedings. The 4th congress was designed primarily to facilitate and update the knowledge in ocular electrophysiology and ocular pharmacokinetics, in both the clinical and preclinical aspects. The outcome of this 4th congress, established in this volume, is a useful contribution to the meth odology in both fields and will hopefully assist in the evaluation and interpretation of ocular findings recorded in animal studies on drugs and other chemicals, in order to protect human health. Undoubtedly, work on the mechanisms of ocular toxicology in the process of pharmaceutical development must continue and these proceedings, embodying the presented papers, will add to the data base. The editors, the congress organizing committee and the members of the International Society of Ocular Toxicology thank the speakers who gave their time, knowledge, and expertise to assist us in this project. The following manuscripts contain the main substance of each of the platform presentations and, in some cases, much more. Moreover, our thanks go to all the participants coming from a range of background- regulatory, academic and industrial -for their attention and excellent contributions during the discussion.

Ocular Toxicology

O. Hockwin

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