Peter Selby

Alistair Ring

Danielle Harari

Janine Mansi

This practical manual in the care of older cancer patients won best oncology book in the BMA Medical Book Awards 2016, and is an essential tool created as a joint project of the Association of Cancer Physicians (ACP) and the British Geriatric Society (BGS). Written by 134 contributors who are all experts in their fields, it offers an overview of the latest developments, with 32 real life case studies. It is a valuable learning and reference resource for doctors, nurses, trainees and other professionals managing cancer in older patients. This evidence-based guidebook will assist the physician in managing the older cancer patient when implementing the appropriate treatment strategy, taking account of comorbidities, frailty, and patient choice. Each clinical case includes a concise discussion on patient presentation and of scenarios underpinning issues experienced by older patients followed by a clear appraisal of how the latest clinical research impacts on patient management. This large cohort of patients requires both innovative care and individual attention, and this carefully crafted book shares the experience of an expert multidisciplinary team in the interest of patient-centred care. It is essential reading for specialists in oncology, specialists in geriatric care, general physicians, doctors in training, oncology nurses, healthcare managers and administrators.

A Case Study Based Reference and Learning Resource

Problem Solving in Older Cancer Patients

Margaret Knowles

. What is cancer?, L.M. Franks and Margaret A. Knowles. 2. The causes of cancer, Naomi Allen, Robert Newton, Amy Berrington de Gonzalez, Jane Green, Emily Banks, and Timothy J. Key. 3. Inherited Susceptibility to Cancer, D. Timothy Bishop. 4. DNA Repair and Cancer, Beate Koberle, John P. Wittschieben, and Richard D. Wood. 5. Epigenetic Events in Cancer, Jonathan C. Cheng and Peter A. Jones. 6. Molecular Cytogenetics of Cancer, Denise. Sheer and Janet Shipley. 7. Oncogenes, Margaret A. Knowles. 8. Tumour suppressor genes, Sonia Lain and David P. Lane. 9. The cancer cell cycle, Chris J. Norbury. 10. Cellular immortalization and telomerase activation in cancer, Robert F. Newbold. 11. Growth factors and their signalling pathways in cancer, Sally A. Prigent. 12. Apoptosis: molecular physiology and significance for cancer therapeutics, Dean A. Fennell. 13. Mechanisms of Viral Carcinogenesis, Paul Farrell. 14. Cytokines and Cancer, Peter W. Szlosarek and Frances R. Balkwill. 15. Hormones and cancer, Charlotte L. Bevan. 16. The spread of tumours, Ian Hart. 17. Angiogenesis, K.Tahtis and R.Bicknell. 18. Stem cells, heamopoiesis, and leukaemia, Mel Greaves. 19. Animal models of cancer, Jos Jonkers and Anton Berns. 20. The immunology of cancer, Peter C. L. Beverley. 21. The molecular pathology of cancer, Tatjana Crnogorac-Jurcevic, Richard Poulsom, and Nicholas R. Lemoine. 22. From transcriptome to proteome, Silvana Debernardi, Rachel Craven, Bryan D. Young, and Rosamonde E. Banks. 23. Local treatment of cancer, Ian S. Fentiman. 24. Chemotherapy, D.R. Camidge and D.I. Jodrell. 25. Radiotherapy and molecular radiotherapy, Anne Kiltie. 26. Monoclonal antibodies and therapy, T. Geldart, M.J. Glennie, and P.W.M. Johnson. 27. Immunotherapy of cancer, Andrew M. Jackson and Joanne Porte. 28. Cancer gene therapy, John David Chester. 29. Screening, Peter Sasieni and Jack Cuzick. 30. Conclusions and prospects, Peter Selby and Margaret A Knowles.

Introduction to the Cellular and Molecular Biology of Cancer

Ruth E Board

Michael I Bennett

Penney Lewis

John Wagstaff

Legal change on the provision of assisted dying by healthcare professionals has occurred in a substantial number of jurisdictions. This work brings together contributions on end of life choices from experienced professionals from oncology disciplines, palliative care, law, nursing and professions allied to medicine. The goals are: • To better inform cancer care professionals and the wider community about developments in choices in end of life care for cancer patients internationally. • To better answer questions from patients and respond to their requests, including questions about and requests for assisted dying in countries where it is legal. • To have a balanced and well-informed dialogue about choices available to patients, without developing a formal policy position on change in law. • To provide a basis of information for future educational activities.

End of Life Choices for Cancer Patients

Peter Selby

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