Scott E. Fishman

Srinivasa N. Raja

Honorio Benzon

Spencer S Liu

Steven P Cohen

This third edition of Essentials of Pain Medicine offers an accessible and concise, yet complete, overview of today's theory and practice of pain medicine and regional anesthesia. From a review of basic considerations through local anesthetics and nerve block techniques, this book provides the reader with an excellent tool for exam review or practice of Pain Management. Organized in a concise, practical quick-reference format. All chapters are brief and easy to read quickly. Offers specific strategies for the evaluation and management of a full range of pain syndromes, including cancer pain. Features over 230 diagrams, illustrations, summary charts and tables that clarify the information and make it easy to apply. Discusses the latest drugs and therapeutic approaches, such as acupuncture. Presents the management of pain for every setting where it is practiced, including the emergency room, the critical care unit, and the pain clinic. Includes new topics such as: imaging in pain medicine, radiation safety, issues associated with the use of narcotics, intraarticular and intraperitoneal use of opioids, pain management in the emergency room and in the intensive care unit, pain management issues during pregnancy, geriatric pain, and hospice care and end-of-life issues. New chapters on interventional procedures include discography, intradiscal electrothermal coagulation (IDET), vertebroplasty, and piriformis injections. Truncal blocks and neuraxial blocks and anticoagulants are added to the section on nerve blocks.

Essentials of Pain Medicine E-book

Scott Dessain

Preserving the Promise: Improving the Culture of Biotech Investment critically examines why most biotech startups fail, as they emerge from universities into an ecosystem that inhibits rather than encourages innovation. This "Valley of Death" squanders our public investments in medical research and with them, the promise of longer and healthier lives. The authors explicate the Translation Gap faced by early stage biotech companies, the result of problematic technology transfer and investment practices, and provide specific prescriptions for improving translation of important discoveries into safe and effective therapies. In Preserving the Promise, Dessain and Fishman build on their collective experience as company founders, healthcare investor (Fishman) and physician/scientist (Dessain). The book offers a forward-looking, critical analysis of "conventional wisdom" that encumbers commercialization practices. It exposes the self-defeating habits of drug development in the Valley of Death, that waste money and extinguish innovative technologies through distorted financial incentives. Explains why translation of biotech discovery into medicine succeeds so infrequently that it’s been dubbed the Valley of Death Uncovers specific decision-making strategies that more effectively align incentives, improving clinical and financial outcomes for investors, inventor/entrepreneurs, and patients Examines the critical, early stages of commercialization, where technology transfer offices and Angels act as gatekeepers to development, and where tension between short-term financial and long-term clinical aspirations sinks important technologies Deconstructs the forces driving biotech, recasts them in a proven conceptual framework, and offers practical guidance for making the system better

Scott E. Fishman

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