Simon Day

Best known as one of the stars of the Fast Show(where he played characters such as Dave Angel -- Eco-Warrior, Tommy Cockles and Competitive Dad) and Bellamy's Peopleco-starring Paul Whitehouse, Simon Day tells the shocking, sometimes sad and hilariously funny story of his life so far. Simon Day's memoir is a story of unlikely successes and secret lives. In the early 1980s he was a petty thief living rough in South East London and stealing whatever he could to fund an addiction to fruit machines. He was arrested and sentenced to borstal. Simon's memoir tells the story of how this nice, middle-class boy from the suburbs -- a self-confessed 'crap criminal' -- served time with the professionals and hard-cases in a jail fiercely divided along racial lines during the height of the 1981 riots. It moves on to the lucky breaks, the talent getting recognised, the 'redemption' of his years as a celebrity . . . with the parallel story of his addiction which -- with money and success -- became fuelled by drugs. Dark and dramatic, Simon Day's memoir is a laugh-out-loud-funny story of drugs, crime and comedy.

They Really Were Marvellous Times

Comedy and Error

Juan Carlos Carracedo

Rising from the floor of the Atlantic the seven Canary Islands are related to a mantle plume or hotspot. The islands' geology is characterized by a wide range of volcanic and intrusive rocks, exposed in spectacular scenery and easily reached by road and on foot. These rocks include all the stage characteristics of oceanic island volcanoes. This clearly written and fully illustrated introductory guide is an essential accompaniment for earth scientists visiting the islands. (Series: Classic Geology in Europe)

Canary Islands

Brian S. Everitt

Stephen George

David Machin

Sylvan Green

A comprehensive volume on clinical trials that covers all important disease and therapeutic areas together with methodologies, phase I/II/III studies and other issues. The volume catalogues the impact of clinical trials on the practice of medicine and discusses the developments and practice of medical statistics. Cancer, cardiovascular disease, dermatological, dental, mental, ophthalmic health, gynaecology and respiratory diseases are all discussed in separate chapters, with discussions on outcome measures, competing risks and statistical models given for each therapy area. It also presents: * A history of clinical trials * A summary of pertinent statistical issues * How to choose a clinical trial design * Ethical constraints and considerations * Clinical trial issues in paediatrics and those involving older patients * Clinical trials in complementary medicine

Textbook of Clinical Trials

Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume. Praise for the First Edition: "... very useful as an introduction to clinical research, or for those planning specific studies within therapeutic or disease areas." BRITISH JOURNAL OF SURGERY, Vol. 92, No. 2, February 2005 The book’s main concept is to describe the impact of clinical trials on the practice of medicine. It separates the information by therapeutic area because the impact of clinical trials, the problems encountered, and the numbers of trials in existence vary tremendously from specialty to specialty. The sections provide a background to the disease area and general clinical trial methodology before concentrating on particular problems experienced in that area. Specific examples are used throughout to address these issues. The Textbook of Clinical Trials, Second Edition: Highlights the various ways clinical trials have influenced the practice of medicine in many therapeutic areas Describes the challenges posed by those conducting clinical trials over a range of medical specialities and allied fields Additional therapeutic areas are included in this Second Edition to fill gaps in the First Edition as the number and complexity of trials increases in this rapidly developing area Newly covered or updated in the Second Edition: general surgery, plastic surgery, aesthetic surgery, palliative care, primary care, anaesthesia and pain, transfusion, wound healing, maternal and perinatal health, early termination, organ transplants, ophthalmology, epilepsy, infectious disease, neuro-oncology, adrenal, thyroid and urological cancers, as well as a chapter on the Cochrane network An invaluable resource for pharmaceutical companies, the Textbook of Clinical Trials, Second Edition appeals to those working in contract research organizations, medical departments and in the area of public health and health science alike.

Alys Daddi

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