Takashi Shimizu

Ran Nir-Paz

Takeshi Saraya

Annemarie Van Rossum

Cécile Bébéar

Mycoplasma pneumoniae (Mp) is a major human pathogen that causes both upper and lower respiratory infections, and is one of the leading causes of community acquired pneumonia (CAP), accounting for 11–15% of CAP throughout the world. Additionally it is known to induce an inflammatory process which depends on several mechanisms such as virulence of Mp (lipoproteins, community acquired respiratory distress syndrome (CARDS) toxin, oxidative products) and host defenses (cellular immunity and humoral immunity). Although it is a common pathogen, the pathogenesis for Mp infections is not yet fully understood. From the clinical point of view, since the pioneer studies in the 1960s and 1970s on the clinical presentation of Mp associated disease, the diagnostics approaches have changed dramatically leading to a better understanding of the clinical presentation and new issues have emerged - such as antibiotics resistance. The purpose of this Frontiers ebook is to thoroughly review and discuss the clinical presentation in view of the improved diagnostics, microbiological and immunological analysis of Mp infections, with focus on the history of Mp, clinical features of disease, bacterial structure of Mp and mechanism of gliding, clinical and laboratory diagnostics, the role of lipoproteins and Toll-like receptor, CARDS toxin, subtyping of Mp isolates and genome analysis, macrolide resistance and treatment.

Mycoplasma pneumoniae Clinical Manifestations, Microbiology, and Immunology

Meimu

In Japan, ju-on is a deadly curse that takes on a life of its own. Always seeking new victims, it's a grudge that doesn't stop-it can't be stopped. Anyone unfortunate enough to meet up with a ghost killed by the grudge is then killed-and so it spreads. When a senior citizen outreach volunteer goes to work in a house in a quiet residential area, she soon starts to hear odd noises. As the strange events get more and more ominous, she discovers that some acts of violence can attach themselves to a house and that some evils can reach out and touch you-even after death.

Ju-On

Miki Rinno

Presents a manga adaptation of the Japanese horror movie that centers on a home and the horrific events that happened there.

Video Side

As the world's third-ranking economic power, Japan's style of management, such as the lifetime employment system, the seniority system, and an enterprise union, has been well studied. However, little else is known about the Japanese management control systems (MCSs) and management accounting systems, which are significantly different from other economic powers. This book sheds light on Japanese MCSs and the differences with those of the United States, illustrated with examples from Mitsubishi Electric, Kao, and more. This book aids not only researchers in management accounting, but also provides more useful insight for international investors and management accountants that can prove useful in business management.

Takashi Shimizu

About

Books

Join the club