Mark de Berg

Ulrich Meyer

This book constitutes the proceedings of the 18th Annual European Symposium on Algorithms, held in Liverpool, UK in September 2010.

18th Annual European Symposium, Liverpool, UK, September 6-8, 2010, Proceedings

Algorithms - ESA 2010

Algorithms -- ESA 2010, Part II

Peter Sanders

Algorithms that have to process large data sets have to take into account that the cost of memory access depends on where the data is stored. Traditional algorithm design is based on the von Neumann model where accesses to memory have uniform cost. Actual machines increasingly deviate from this model: while waiting for memory access, nowadays, microprocessors can in principle execute 1000 additions of registers; for hard disk access this factor can reach six orders of magnitude. The 16 coherent chapters in this monograph-like tutorial book introduce and survey algorithmic techniques used to achieve high performance on memory hierarchies; emphasis is placed on methods interesting from a theoretical as well as important from a practical point of view.

Advanced Lectures

Algorithms for Memory Hierarchies

The theory of relativity convinced many philosophers that space and time are fundamentally alike, and that they are mere aspects of a more fundamental space-time. Ulrich Meyer argues against this consensus view. Instead of a 'spatial' account of time that treats instants like positions in space, he presents the first comprehensive defense of a 'modal' account that emphasizes the similarities between times and the possible worlds in modal logic. Contrary to popularbelief, such an account does not commit us to the view that there is something metaphysically special about the present moment, and is easily reconciled with the theory of relativity.

The Nature of Time

Jop Sibeyn

This is the first volume in an interdisciplinary three-book series covering the full range of biological, clinical, and surgical aspects in the evaluation, diagnosis, and treatment of patients with craniofacial malformations. This volume opens by considering general topics such as developmental biology and disease classification and then examines in depth the biological basis of the various malformations, including craniosynostoses, cleft-lip and palate with complex orofacial clefts, branchio-oculo-facial syndromes, rare syndromes, soft tissue malformations, and dysgnathia. Psychological aspects, including psychological evaluation methods and therapies and quality of life issues, are then addressed. Finally, all relevant clinical, radiological, and genetic investigations are described and important diagnostic issues are explored. Featuring numerous high-quality illustrations, the book will be of high value for all clinicians, researchers, and postgraduate students who deal with these malformations. The accompanying two volumes describe treatment principles and present in an atlas manner all relevant surgical techniques in detail. The content of this multivolume set, written by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this medical field.

Vol. 1, Disease and Diagnostics

Fundamentals of Craniofacial Malformations

Hans Peter Wiesmann

Bone and Cartilage Engineering provides a complete overview of recent knowledge in bone and cartilage tissue engineering. It follows a logical approach to the various aspects of extracorporal bone and cartilage tissue engineering. The cooperation between a basic scientist and a clinician made it possible to structure the book's content and style according to the interdisciplinary character of the field. The comprehensive nature of the book, including detailed descriptions of laboratory procedures, preclinical approaches, clinical applications, and regulatory issues, will make it an invaluable basis for everyone working in this field. This book will serve as a fundamental tool for basic researchers to establish or refine tissue engineering techniques as well as for clinicians to understand and use this modern therapeutic option.

Bone and Cartilage Engineering

Thomas Meyer

Jörg Handschel

"Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are in the preclinical testing phase. Because of these developments, there is a need to provide comprehensive and detailed information for researchers and clinicians on this rapidly expanding field. This book offers, in a single volume, the prerequisites of a comprehensive understanding of tissue engineering and regenerative medicine. The book is conceptualized according to a didactic approach (general aspects: social, economic, and ethical considerations; basic biological aspects of regenerative medicine: stem cell medicine, biomolecules, genetic engineering; classic methods of tissue engineering: cell, tissue, organ culture; biotechnological issues: scaffolds; bioreactors, laboratory work; and an extended medical discipline oriented approach: review of clinical use in the various medical specialties). The content of the book, written in 68 chapters by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this bio-medical field.

Ulrich Meyer

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