Exit Through the Wound

24-year-old Maine works a thankless graduate job, takes too many recreational and prescription drugs and spends too much of his wealthy parents' money. He finds a kindred spirit in Sadie, a rich American girl now living in London with her male model boyfriend, Guy. Disillusioned with the life they have chosen, Maine and Sadie attempt to escape the boredom of city life through decadence and excess. And Maine begins to fall in love. But when he is struck by a neurological disease, he is forced to question whether his lifestyle is actually causing the melancholy he's fighting.