Joseph Zohar

Thomas R. Insel

Steven A. Rasmussen

The Psychobiology of Obsessive-compulsive Disorder

A clear summary of what is known about a highly prevalent and debilitating disorder that affects nearly as many people as does asthma. Expert authors review the biological basis for the disorder and describe both pharmacological and psychological approaches to treatment.

Current Science and Clinical Practice

Obsessive Compulsive Disorder

Michele Tortora Pato

During the 10 years since publication of the first edition of this comprehensive volume, progress in neuroscience has had direct and immediate clinical implications in both the pharmacological and psychological arenas in the treatment of one of psychiatry's greatest challenges: obsessive-compulsive disorder (OCD). This second edition reflects this progress. Chapters include the latest data on the use of all current OCD treatments in special populations, such as the strictly religious, the elderly, children, adolescents, and those who are pregnant, and all are illustrated with new and updated detailed case histories that highlight specific treatments and diagnostic issues. This edition includes Three new pharmacotherapy chapters that discuss the use of sertraline, paroxetine, and citalopram and updates of the original edition's chapters on clomipramine, fluoxetine, and fluvoxamine An expanded chapter on children and adolescents that emphasizes the benefits of early detection, and describes the latest findings in immunological research with particular regard to pediatric autoimmune neurologic disorders associated with streptococcal infection (PANDAS) An expanded behavioral therapy chapter that encompasses not only detailed treatment plans for both individuals and groups (including multifamily groups) but also up-to-date empirical data to support their use The latest data on compounds for treating OCD (twice the number of compounds are now available than when the first edition was published), including details of the dramatic increase in our knowledge of pharmacokinetics, receptor profiles, interactions, and comparative efficacy during the past decade The clinical implications of today's broadened definition of OCD, which includes disorders such as body dysmorphic disorder, trichotillomania, pathological gambling, and Tourette's syndrome, and the complicated diagnostic and management issues -- with a call for innovative treatment approaches -- raised by the intimate relationship between OCD and schizophrenia (15% of patients with schizophrenia also have OCD) A multidisciplinary approach to treatment-resistant OCD, which occurs in approximately 30% of all cases, suggesting ways to combine our current knowledge and focus it on the treatment of a specific individual With their extensive clinical and research experience in treating OCD, the distinguished contributors to this volume provide clinicians with the latest, most reliable data so that they may better match treatment approaches with each patient's unique needs. Of enduring practical value, this updated "how to" manual will be welcomed by all clinicians treating patients with OCD, as well as students and other interested clinicians, as an effective tool in the ongoing challenge to understand and treat this frustrating disorder.

Current Treatments of Obsessive-Compulsive Disorder

David Nutt

Eric J. L. Griez

Carlo Faravelli

This book will be a practical textbook based on the courses held for the European Certificate in Anxiety and Mood Disorders. The Certificate is an international post graduate programme in the field of affective disorders and the course provides an update of knowledge and analyses the most recent developments. This book will be obligatory reading for the courses and will also be suitable for all psychiatric residents.

An Introduction to Clinical Management and Research

Anxiety Disorders

Neuroscience Based Nomenclature

NbNomenclature

Norman Sartorius

Mario Maj

Ahmed Okasha

Obsessive-compulsive disorder is probably the psychiatric disorder for which most significant progress has been made on the last 20 years concerning pharmacologic and psychotherapeutic interventions. A number of studies have shown that OCD is much more prevalent than previously thought, occurring in an estimated 2% of the adult population around the world. A serious discrepancy still exists between research evidence and clinical practice and an update of this evidence and an international debate on it, as provided by this volume, is long overdue. This revised edition provides vital information on a considerably underdiagnosed condition. * Provides accompanying commentaries by an outstanding line up of contributors * Covers developments in diagnosis, therapy, prognosis, economic evaluation and quality improvement * Provides an unbiased and reliable reference point

Obsessive-Compulsive Disorder

Obsessive compulsive disorder (OCD) remains one of the most challenging disorders of the brain. Contemporary conceptualization and therapeutic strategies are undergoing a revolution as a result of new insights derived from modern technological advances. This book was conceived in order to present this revolution to the reader. It covers current theories regarding the etiology of OCD, what is known about the genetics of this disorder, evidence from neuroimaging and a discussion of potential endophenotypes. There is an evaluation of current treatment approaches for the disorder, encompassing psychological, psychopharmacological and physical interventions, as well as a discussion of treatment resistance. The book considers methodological issues, plus reviews of OCD in pediatric populations. A summary chapter highlights some potential research avenues, in a discussion of the future directions in OCD. Rather than provide comprehensive coverage, repeating material from standard psychiatry textbooks, this book focuses on recent information and its application, distinguishing it from other titles. If you work in children with OCD, If you are interested in genetics, neurocognition or brain imaging, If you work with patients and would like to improve your assessment in OCD and OCD Spectrum disorders, to update your therapeutic strategies and to get a handle on cutting edge developments in this intriguing field, If you are planning a research project in OCD and would like to get some hints from people who are research leaders in this field and also learn about methodological issues specific to OCD research, then this book will be a valuable resource. A concise overview of the current state of the art in OCD assessment and treatment, including physical interventions and treatment resistance Focuses on scientific advances (including specific methodological issues) and how they can inform and benefit clinical practice Looks critically and broadly at the diagnostic classification, including the ongoing revision of the two major international systems Written by an A-list team of experts in the field who have a track record of being engaging authors

Joseph Zohar

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