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Michael Oldstone

About

Michael Beaureguard Alan Oldstone was an American virologist and immunologist known for his work on viral pathogenesis, a field of which he is considered one of the founders. He and his group originated several important concepts, including molecular mimicry, disease associated with immune complexes, and the idea that persistent viruses can alter cellular functioning in significant ways. His research focused on RNA viruses that infect animals, particularly lymphocytic choriomeningitis virus but also influenza virus, measles virus and others, often using mouse models of infection. Oldstone spent his entire research career at the Scripps Research Institute (1966–2019). In addition to his academic writing, he published the general-audience book, Viruses, Plagues, and History (1998).