Richard Mayne

Jaap den Toonder

Cilia are microscopic finger-like cell-surface organelles possessed by a great many eukaryotic organisms, including humans, whose purposes include generating local fluid movements via rhythmic whip-like beating and environmental sensing. Despite intense research efforts since their discovery by van Leeuwenhoek in the 1670's, several key questions regarding ciliary functions, experimental manipulation and in silico imitation remain unanswered. Major justifications for cilia research lie in their involvement in various forms of human disease (ciliopathies) and their ability to instantiate decentralised, asynchronous sensorial-actuation of adjacent matter through modulation of beating characteristics. Further elucidation of these characteristics, which is a problem requiring the combined expertise of mathematicians, computer scientists, engineers and life scientists, will lead to novel biomedical therapies, creation of `smart' actuating surfaces for microfluidics/lab-on-chip applications and a greater understanding of fluid mechanics in real-world scenarios. This lavishly-illustrated anthology presents recent advances in the fields of ciliary investigation, manipulation, emulation, mimesis and modelling from key researchers in their fields: its goal is to explain the state-of-the-art in cilia bioengineering and bio-computation in a uniquely creative, accessible manner, towards encouraging further transdisciplinary work in the field as well as educating a broad spectrum of scientists and lay people. The volume is split into three distinct but interwoven themes:Biology: Biological preliminaries for the study of cilia; the state-of-the-art in genetic engineering of ciliated cells for biomedical purposes; reprogramming of cilia dynamics in live cells.Engineering: Creation of macro cilia robots for object sorting applications; pneumatic cilia for the optimization of fluid motion; electrostatic, magnetic and MEMS cilia for microfluidic mixing; reviews in artificial cilia fabrication, actuation and flow induction methods.Numerical and computational modelling. Analyses of thin film cilia for `lab on chip' microfluidic mixing applications; modelling of gel-based artificial cilia towards simulating dynamic behaviors of responsive cilia layers in complex fluids across a wide range of potential applications.

Atlas of Cilia Bioengineering and Biocomputing

Writer, international civil servant, broadcaster and critic, Richard Mayne wrote The Copper Stick as a record for his children. His family has published these memoirs to share this story of a remarkable life. A tale of growing up in 1930s London, of being billeted during the war and educated at St Pauls and Cambridge, The Copper Stick charts a brief spell in Egypt with the army and his career with Jean Monnet, the founding father of the European Union. His lifelong passion for the EU illuminate the tales of his many roles helping lead it, and his days as a journalist, broadcaster and critic. Full of wonderful anecdotes, vivid detail and many colourful characters, this is also the story of a much loved, missed and admired family man.

The Copper Stick

First Published in 2000. Routledge is an imprint of Taylor & Francis, an informa company.

The Language of Sailing

Robert Tombs

Douglas Johnson

This book explores the understandings and misunderstandings that make up the Entente Cordiale - the hundred-year relationship, as well as the everyday common interests and shared pleasures that give it substance.

100 Years of the Entente Cordiale

Cross Channel Currents

Discussion of the beginnings, workings and future of the European Economic Community.

The Community of Europe

Wilton Park is not a stately home. It was once. In World War II it became a secret camp for interrogating enemy generals. But it took on its true, unique role in 1946 as a training centre for German prisoners-of-war. Later, it carried out the civic education of civilians due to help run post-war Germany. Before long, it opened its doors to high-flyers from other European countries, the United States and the rest of the world. It still flourishes as a forum in which policy makers and opinion formers from politics, government, business and the professions discuss in private the best ways of solving international problems and increasing understanding.

A History of Wilton Park

In Victory, Magnanimity, in Peace, Goodwill

Postwar, the Dawn of Today's Europe

A guide to the vocabulary of sailing provides a history of the sport's terms and their use in everyday language.

Richard Mayne

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